Evidence map›Paper›PMID 33535779›Full record

ArticleStroke2021

Acute Ischemic Stroke and COVID-19: An Analysis of 27 676 Patients.

Adnan I Qureshi, William I Baskett, Wei Huang, Daniel Shyu, Danny Myers, Murugesan Raju, Iryna Lobanova, M Fareed K Suri, S Hasan Naqvi, Brandi R French and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 5 pooled it
29.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 5 syntheses or guidelines pooled it, 306 citations in OpenAlex.

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112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Adnan I QureshiZeenat Qureshi Institute, St Cloud, MN (A.I.Q, W.H., I.L.).
William I BaskettInstitute for Data Science and Informatics (W.I.B., M.R., C.-R.S.), University of Missouri, Columbia.
Wei HuangZeenat Qureshi Institute, St Cloud, MN (A.I.Q, W.H., I.L.).
Daniel ShyuDepartment of Medicine (D.S.), University of Missouri, Columbia.
Danny MyersTiger Institute for Health Innovation, Cerner Corporation, Columbia, MO (D.M.).
Murugesan RajuInstitute for Data Science and Informatics (W.I.B., M.R., C.-R.S.), University of Missouri, Columbia.
Iryna LobanovaDepartment of Neurology (A.I.Q., W.H., I.L., B.R.F., C.R.G.), University of Missouri, Columbia.
M Fareed K SuriSt. Cloud Hospital, MN (M.F.K.S.).
S Hasan NaqviDepartment of Internal Medicine (S.H.N.), University of Missouri, Columbia.
Brandi R FrenchDepartment of Neurology (A.I.Q., W.H., I.L., B.R.F., C.R.G.), University of Missouri, Columbia.
Farhan SiddiqDivision of Neurosurgery (F.S.), University of Missouri, Columbia.
Camilo R GomezDepartment of Neurology (A.I.Q., W.H., I.L., B.R.F., C.R.G.), University of Missouri, Columbia.
Chi-Ren ShyuInstitute for Data Science and Informatics (W.I.B., M.R., C.-R.S.), University of Missouri, Columbia.
University of Missouri · USCentraCare Health System · USCerner (United States) · USFarhangian University · IRInstitute for Environmental Management · USSt. Cloud Hospital · USUnited States Nuclear Regulatory Commission · US

Funding

Massive and Complex Data Analytics Pre-Doctoral Training in One HealthT32LM012410 · NLM · UNIVERSITY OF MISSOURI-COLUMBIA · PI SHYU, CHI-REN · 2016 to 2020
$1.2M
NIH HHS 5T32LM012410NLM NIH HHS T32 LM012410
6 · The paper itself

Abstract

background and purposeAcute ischemic stroke may occur in patients with coronavirus disease 2019 (COVID-19), but risk factors, in-hospital events, and outcomes are not well studied in large cohorts. We identified risk factors, comorbidities, and outcomes in patients with COVID-19 with or without acute ischemic stroke and compared with patients without COVID-19 and acute ischemic stroke.

methodsWe analyzed the data from 54 health care facilities using the Cerner deidentified COVID-19 dataset. The dataset included patients with an emergency department or inpatient encounter with discharge diagnoses codes that could be associated to suspicion of or exposure to COVID-19 or confirmed COVID-19.

resultsA total of 103 (1.3%) patients developed acute ischemic stroke among 8163 patients with COVID-19. Among all patients with COVID-19, the proportion of patients with hypertension, diabetes, hyperlipidemia, atrial fibrillation, and congestive heart failure was significantly higher among those with acute ischemic stroke. Acute ischemic stroke was associated with discharge to destination other than home or death (relative risk, 2.1 [95% CI, 1.6-2.4];

conclusionsAcute ischemic stroke was infrequent in patients with COVID-19 and usually occurs in the presence of other cardiovascular risk factors. The risk of discharge to destination other than home or death increased 2-fold with occurrence of acute ischemic stroke in patients with COVID-19.

Indexed as

Hospital MortalityAcute Kidney InjuryAdultAgedAged, 80 and overAtrial FibrillationBlack or African AmericanBrain EdemaCerebral HemorrhageCohort StudiesComorbidityCOVID-19Diabetes MellitusFemaleHeart FailureHispanic or Latinocoronavirusdeathelectronic health recordsischemic strokemorbidity

Identifiers

PMID33535779
PMCPMC7903982
OpenAlexW3128412820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.