Evidence map›Paper›PMID 33535778›Full record

Observational studyStroke2021

Integrated Stroke System Model Expands Availability of Endovascular Therapy While Maintaining Quality Outcomes.

Victor Lopez-Rivera, Sergio Salazar-Marioni, Rania Abdelkhaleq, Sean I Savitz, Alexandra L Czap, Yazan J Alderazi, Peng R Chen, James C Grotta, Spiros L Blackburn, Wesley Jones and 9 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Stroke, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Annual Endovascular Thrombectomy Case Volume and Thrombectomy-capable Hospitals of Korea in Acute Stroke Care.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Victor Lopez-RiveraDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Sergio Salazar-MarioniDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Rania AbdelkhaleqDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Sean I SavitzDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Alexandra L CzapDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Yazan J AlderaziDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Peng R ChenDepartment of Neurosurgery (P.R.C., S.L.B., W.J., M.J.D., J.C., D.H.K., A.L.D.), UTHealth McGovern Medical School, Houston, TX.
James C GrottaClinical Innovation and Research Institute, Memorial Hermann Hospital, Texas Medical Center, Houston (J.C.G.).
Spiros L BlackburnDepartment of Neurosurgery (P.R.C., S.L.B., W.J., M.J.D., J.C., D.H.K., A.L.D.), UTHealth McGovern Medical School, Houston, TX.
Wesley JonesDepartment of Neurosurgery (P.R.C., S.L.B., W.J., M.J.D., J.C., D.H.K., A.L.D.), UTHealth McGovern Medical School, Houston, TX.
Gary SpiegelDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Mark J DannenbaumDepartment of Neurosurgery (P.R.C., S.L.B., W.J., M.J.D., J.C., D.H.K., A.L.D.), UTHealth McGovern Medical School, Houston, TX.
Tzu-Ching WuDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Joseph CochranDepartment of Neurosurgery (P.R.C., S.L.B., W.J., M.J.D., J.C., D.H.K., A.L.D.), UTHealth McGovern Medical School, Houston, TX.
Dong H KimDepartment of Neurosurgery (P.R.C., S.L.B., W.J., M.J.D., J.C., D.H.K., A.L.D.), UTHealth McGovern Medical School, Houston, TX.
Arthur L DayDepartment of Neurosurgery (P.R.C., S.L.B., W.J., M.J.D., J.C., D.H.K., A.L.D.), UTHealth McGovern Medical School, Houston, TX.
Grace FarquharSouthEast Texas Regional Advisory Council, Houston (G.F.).
Louise D McCulloughDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
Sunil A ShethDepartment of Neurology (V.L.-R., S.S.-M., R.A., S.I.S., A.L.C., Y.J.A., G.S., T.-C.W., L.D.M., S.A.S.), UTHealth McGovern Medical School, Houston, TX.
The University of Texas Health Science Center · USAdvisory Board Company (United States) · USMemorial Hermann · US

Funding

Gender Differences in Ischemic Cell DeathR01NS055215 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCCULLOUGH, LOUISE D. · 2007 to 2016
$4.3M
Development of a Wireless Endovascular Nerve Stimulator for Treatment of Refractory Neuropathic PainU18EB029353 · NIBIB · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KAN, PETER TZE MAN, ROBINSON, JACOB T. · 2019 to 2019
$2.3M
Deep Learning Enabled Endovascular Stroke Therapy Screening in Community HospitalsR01NS121154 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GIANCARDO, LUCA, SHETH, SUNIL · 2021 to 2025
$2.2M
Role of THSD1 and its Disease Causing Variants in Intracranial AneurysmR01NS104280 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HAGAN, JOHN PATRICK · 2018 to 2022
$1.7M
Role of Haptoglobin Genotype on Neuroinflammation and Coagulation Following Aneurysmal Subarachnoid HemorrhageK23NS106054 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BLACKBURN, SPIROS · 2018 to 2022
$875k
NIBIB NIH HHS U18 EB029353NINDS NIH HHS K23 NS106054NINDS NIH HHS R01 NS055215NINDS NIH HHS R01 NS104280NINDS NIH HHS R01 NS121154
6 · The paper itself

Abstract

background and purposeThe optimal endovascular stroke therapy (EVT) care delivery structure is unknown. Here, we present our experience in creating an integrated stroke system (ISS) to expand EVT availability throughout our region while maintaining hospital and physician quality standards.

methodsWe identified all consecutive patients with large vessel occlusion acute ischemic stroke treated with EVT from January 2014 to February 2019 in our health care system. In October 2017, we implemented the ISS, in which 3 additional hospitals (4 total) became EVT-performing hospitals (EPHs) and physicians were rotated between all centers. The cohort was divided by time into pre-ISS and post-ISS, and the primary outcome was time from stroke onset to EPH arrival. Secondary outcomes included hospital and procedural quality metrics. We performed an external validation using data from the Southeast Texas Regional Advisory Council.

resultsAmong 513 patients with large vessel occlusion acute ischemic stroke treated with EVT, 58% were treated pre-ISS and 43% post-ISS. Over the study period, EVT procedural volume increased overall but remained relatively low at the 3 new EPHs (<70 EVT/y). After ISS, the proportion of patients who underwent interhospital transfer decreased (46% versus 37%;

conclusionsIn our system, increasing EVT availability decreased time from stroke onset to EPH arrival. The ISS provides a framework to maintain quality in lower volume hospitals.

Indexed as

AgedBrain IschemiaEndovascular ProceduresFemaleHemorrhageHospitalsHumansIschemic StrokeMaleMiddle AgedProspective StudiesRegression AnalysisReproducibility of ResultsStrokeThrombectomyTreatment Outcomeacute ischemic strokeendovascular techniqueshealth care deliveryhealth occupations manpowerintegrated delivery systems

Identifiers

PMID33535778
PMCPMC7902449
OpenAlexW3126952498

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.