Evidence map›Paper›PMID 33535719›Full record

ArticlePharmaceutics2021

Visual Acuity Gain Profiles and Anatomical Prognosis Factors in Patients with Drug-Naive Diabetic Macular Edema Treated with Dexamethasone Implant: The NAVEDEX Study.

Mauricio Pinto, Thibaud Mathis, Pascale Massin, Jad Akesbi, Théo Lereuil, Nicolas Voirin, Frédéric Matonti, Franck Fajnkuchen, John Conrath, Solange Milazzo and 12 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 12 institutions in 1 country.

Mauricio PintoDepartment of Ophthalmology, Croix-Rousse University Hospital, 69004 Lyon, France.
Thibaud MathisDepartment of Ophthalmology, Croix-Rousse University Hospital, 69004 Lyon, France.
Pascale MassinDepartment of Ophthalmology, Lariboisière Hospital (AP-HP), University Paris 7 (Sorbonne Paris Cité), 75007 Paris, France.
Jad AkesbiQuinze-Vingt National Eye Hospital, 75012 Paris, France.
Théo LereuilDepartment of Ophthalmology, Croix-Rousse University Hospital, 69004 Lyon, France.
Nicolas VoirinEPIMOD, Epidemiology and Modelling, 01240 Dompierre sur Veyle, France.
Frédéric MatontiDepartment of Ophthalmology, Marseille North Hospital, 13015 Marseille, France.
Franck FajnkuchenDepartment of Ophthalmology, Avicenne Hospital, 93022 Bobigny, France.
John ConrathDepartment of Ophthalmology, Monticelli's Clinic, 13008 Marseille, France.
Solange MilazzoDepartment of Ophthalmology, University Hospital of Amiens-Picardie, 80021 Amiens, France.
Jean-François KorobelnikDepartment of Ophtalmology, Bordeaux University Hospital, 33000 Bordeaux, France.ORCID 0000-0002-4438-9535
Stéphanie BaillifDepartment of Ophthalmology, University Hospital Pasteur 2, 06000 Nice, France.
Philippe DenisDepartment of Ophthalmology, Croix-Rousse University Hospital, 69004 Lyon, France.
Catherine Creuzot-GarcherDepartment of Ophthalmology, University Hospital François Mitterrand, 21000 Dijon, France.
Mayer SrourDepartment of Ophthalmology, Creteil Intercommunal Hospital, University Paris Est Creteil, 94000 Creteil, France.ORCID 0000-0002-3333-8441
Bénédicte DupasDepartment of Ophthalmology, Lariboisière Hospital (AP-HP), University Paris 7 (Sorbonne Paris Cité), 75007 Paris, France.ORCID 0000-0002-8335-5223
Aditya SudhalkarAlphavision Augenzentrum, 27570 Bremerhaven, Germany.
Alper BilgicAlphavision Augenzentrum, 27570 Bremerhaven, Germany.ORCID 0000-0001-8403-0853
Ramin TadayoniDepartment of Ophthalmology, Lariboisière Hospital (AP-HP), University Paris 7 (Sorbonne Paris Cité), 75007 Paris, France.
Eric H SouiedDepartment of Ophthalmology, Creteil Intercommunal Hospital, University Paris Est Creteil, 94000 Creteil, France.
Corinne DotDepartment of Ophthalmology, Desgenettes Military Hospital, 69003 Lyon, France.ORCID 0000-0003-4398-3978
Laurent KodjikianDepartment of Ophthalmology, Croix-Rousse University Hospital, 69004 Lyon, France.ORCID 0000-0002-3908-6716
Hôpital de la Croix-Rousse · FRUniversité Paris Cité · FRCentre National de la Recherche Scientifique · FRDélégation Provence et Corse · FRUniversité Paris-Est Créteil · FRCentre hospitalier national d'ophtalmologie des Quinze-Vingts · FRCentre Hospitalier Universitaire Amiens-Picardie · FRHôpital Avicenne · FRHôpital Pasteur · FRMaison des Sciences sociales et des Humanités de Dijon · FRService de Santé des Armées · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study is to evaluate the visual acuity (VA) gain profiles between patients with drug-naive diabetic macular edema (DME) treated by dexamethasone implant (DEX-implant) and assess the baseline anatomical and functional factors that could influence the response to the treatment in real-life conditions. A retrospective, multi-center observational study included 129 eyes with drug-naive DME treated by DEX-implant. The Median follow-up was 13 months. Two groups of VA gain trajectories were identified-Group A, with 71% (

Indexed as

dexamethasone-implantdiabetic macular edemavisual acuity gain

Identifiers

PMID33535719
PMCPMC7912784
OpenAlexW3126285770

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.