Evidence map›Paper›PMID 33535691›Full record

ReviewJournal of clinical medicine2021

Potential Application of Cardiac Computed Tomography for Early Detection of Coronary Atherosclerosis: From Calcium Score to Advanced Atherosclerosis Analysis.

Edoardo Conte, Saima Mushtaq, Davide Marchetti, Vincenzo Mallia, Marta Belmonte, Eleonora Melotti, Gianluca Pontone, Mauro Pepi, Daniele Andreini

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Utility of Cardiovascular CT in Ischemic Heart Disease.Echocardiography (Mount Kisco, N.Y.) · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Edoardo ConteDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino, IRCCS, University of Milan, 20100 Milan, Italy.
Saima MushtaqDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino, IRCCS, University of Milan, 20100 Milan, Italy.
Davide MarchettiDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino, IRCCS, University of Milan, 20100 Milan, Italy.
Vincenzo MalliaDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino, IRCCS, University of Milan, 20100 Milan, Italy.
Marta BelmonteDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino, IRCCS, University of Milan, 20100 Milan, Italy.
Eleonora MelottiDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino, IRCCS, University of Milan, 20100 Milan, Italy.
Gianluca PontoneDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino, IRCCS, University of Milan, 20100 Milan, Italy.ORCID 0000-0002-1339-6679
Mauro PepiDepartment of Cardiovascular Imaging, Centro Cardiologico Monzino, IRCCS, University of Milan, 20100 Milan, Italy.ORCID 0000-0003-2524-6288
Daniele AndreiniDepartment of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, 20100 Milan, Italy.
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present article, an overview of advanced analysis of coronary atherosclerosis by coronary computed tomography angiography (CCTA) is provided, focusing on the potential application of this technique in a primary prevention setting. Coronary artery calcium score (CACS) has a well-demonstrated prognostic value even in a primary prevention setting; however, fibro-fatty, high-risk coronary plaque may be missed by this tool. On the contrary, even if not recommended for primary prevention in the general population, CCTA may enable early high-risk atherosclerosis detection, and specific subgroups of patients may benefit from its application. However, further studies are needed to determine the possible use of CCTA in a primary prevention setting.

Indexed as

coronary artery calcium scorecoronary computed tomography angiographyhigh-risk plaque featuresprimary preventionquantitative coronary plaque analysis

Identifiers

PMID33535691
PMCPMC7867151
OpenAlexW3128451233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.