ReviewPathogens (Basel, Switzerland)2021
Leptospiral Infection, Pathogenesis and Its Diagnosis-A Review.
Review in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Systematic review of the prevalence of environmental and host-related risk factors and the zoonotic potential of leptospirosis in domestic dogs in regions impacted by environmental changes.BMC veterinary research · 2025Pooled it
- Prevalence of Anti-Leptospira Antibodies in Bovines (2018-2023) and Reported Serovars and Serogroups-A Systematic Review With Meta-Analysis.Veterinary medicine and science · 2025Pooled it
- Prevalence of dengue and leptospirosis coinfection and associated mortality rates: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Leptospirosis in humans and selected animals in Sub-Saharan Africa, 2014-2022: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- Molecular epidemiology of pathogenic Leptospira spp. in Thailand during 2024-2025, with detection of Leptospira weilii in human clinical specimens.PLoS neglected tropical diseases · 2026Article
- First report of seropositivity to pathogenic Leptospira in backyard hens: potential poultry health issue and zoonotic risk.Poultry science · 2026Article
- Genetic Diversity ofPathogens (Basel, Switzerland) · 2026Article
- Eco-Epidemiological Study of Seropositivity Against Rickettsia and Leptospira Agents in Rural Areas of Urabá, Colombia.Tropical medicine & international health : TM & IH · 2026Article
- Leptospirosis presenting with fever, jaundice, and generalized lymphadenopathy: a case report with diagnostic challenges.Annals of medicine and surgery (2012) · 2026Article
- Leptospirosis-associated acute kidney injury in Odisha, India.International urology and nephrology · 2026Article
- Diagnostic Performance of Two Commercial qPCR Kits forTropical medicine and infectious disease · 2026Article
- Pathogens of the Human Central Nervous System- the Major Bacterial Pathogens.Molecular neurobiology · 2026Review
- Revisiting genital leptospirosis in large animals: impacts on reproductive health, diagnostic challenges, and future directions.Journal of clinical microbiology · 2026Review
- Retrospective Molecular Detection and Characterization of PathogenicTropical medicine and infectious disease · 2026Article
- Clinical and sero-diagnosis of feline leptosprosis in the sleman region of Yogyakarta, Indonesia.Open veterinary journal · 2026Article
- Severe Leptospirosis With Multi-Organ Dysfunction Syndrome in a Non-Endemic Region: A Case Report.Cureus · 2026Article
- Evaluation of a recombinant Loa22-gold nanoparticle based lateral flow assay for the serodiagnosis of leptospirosis in canine and bovine.Archives of microbiology · 2026Article
- Autoimmune Hemolytic Anemia Associated With Leptospirosis: A Rare Complication.HCA healthcare journal of medicine · 2026Article
- Review
- Detection of pathogenic leptospires in water bodies in neighborhoods vulnerable to flooding, through a participatory research approach in Santa Fe (Argentina).PLOS global public health · 2026Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptospirosis is a perplexing conundrum for many. In the existing literature, the pathophysiological mechanisms pertaining to leptospirosis is still not understood in full. Considered as a neglected tropical zoonotic disease, leptospirosis is culminating as a serious problem worldwide, seemingly existing as co-infections with various other unrelated diseases, including dengue and malaria. Misdiagnosis is also common as non-specific symptoms are documented extensively in the literature. This can easily lead to death, as the severe form of leptospirosis (Weil's disease) manifests as a complex of systemic complications, especially renal failure. The virulence of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.