Evidence map›Paper›PMID 33535603›Full record

ReviewToxins2021

Animal Venom for Medical Usage in Pharmacopuncture in Korean Medicine: Current Status and Clinical Implication.

Soo-Hyun Sung, Ji-Won Kim, Ji-Eun Han, Byung-Cheul Shin, Jang-Kyung Park, Gihyun Lee

Abstract readReview
In one paragraph

Review in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Effectiveness ofToxins · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Effect ofMolecules (Basel, Switzerland) · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Inhibitors of ATP Synthase as New Antibacterial Candidates.Antibiotics (Basel, Switzerland) · 2023
    Review
  15. Review
  16. Article
  17. 5-HTThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Soo-Hyun SungDepartment of Policy Development, National Development Institute of Korean Medicine, Seoul 04554, Korea.ORCID 0000-0001-7606-0147
Ji-Won KimDepartment of Policy Development, National Development Institute of Korean Medicine, Seoul 04554, Korea.
Ji-Eun HanDepartment of Policy Development, National Development Institute of Korean Medicine, Seoul 04554, Korea.
Byung-Cheul ShinDivision of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Korea.ORCID 0000-0002-0059-2689
Jang-Kyung ParkDivision of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Korea.ORCID 0000-0002-4323-278X
Gihyun LeeCollege of Korean Medicine, Dongshin University, Naju 58245, Korea.ORCID 0000-0001-6250-8852

Funding

Ministry of Health and Welfare Accreditation of External Herbal Dispensaries of Traditional Korean Medicine Clinics
6 · The paper itself

Abstract

Animal venoms, widespread throughout the world, are complex mixtures, the composition of which depends on the venom-producing species. The objective of this study was to contribute to the development of animal venom-based medicines by investigating the use of animal venom pharmacopuncture in Korean medicine (KM) institutions. We surveyed 256 public health centers from 1 through 31 October 2019 as guided by the Ministry of Health and Welfare (MoHW). A questionnaire developed by an expert group was distributed and collected for statistical analysis. The survey identified three types of animal venom-based pharmacopuncture: bee, snake, and toad venoms. The medications are based on a single animal venom ingredient and produced in 11 external herbal dispensaries (EHDs). Each animal venom is processed, refined, and freeze-dried in a cleanroom to produce a powder formulation that is later measured, diluted, filtered, filled, sealed, sterilized, and packaged as pharmacopuncture injections used in KM institutions. Bee venom therapy is effective in treating musculoskeletal pain, snake venom therapy is effective in controlling bleeding during surgery, and toad venom therapy is effective in cancer treatment. The study suggests that bee, snake, and toad venoms could be used in medical institutions and have the potential for drug development.

Indexed as

Acupuncture TherapyMedicine, Korean TraditionalAmphibian VenomsAnimalsBee VenomsHumansRepublic of KoreaSnake VenomsTreatment OutcomeAmphibian VenomsBee VenomsSnake Venomsanimal venombee venompharmacopuncturesnake venomtoad venom

Identifiers

PMID33535603
PMCPMC7912904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.