Evidence map›Paper›PMID 33535561›Full record

ArticleInternational journal of molecular sciences2021

Radiation Response of Cervical Cancer Stem Cells Is Associated with Pretreatment Proportion of These Cells and Physical Status of HPV DNA.

Irina Zamulaeva, Elena Selivanova, Olga Matchuk, Valentina Kiseleva, Liana Mkrtchyan, Ludmila Krikunova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Irina ZamulaevaDepartment of Radiation Biochemistry, A. Tsyb Medical Radiological Research Center-Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Korolev str.-4, 249036 Obninsk, Russia.ORCID 0000-0002-6136-8445
Elena SelivanovaDepartment of Radiation Biochemistry, A. Tsyb Medical Radiological Research Center-Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Korolev str.-4, 249036 Obninsk, Russia.
Olga MatchukDepartment of Radiation Biochemistry, A. Tsyb Medical Radiological Research Center-Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Korolev str.-4, 249036 Obninsk, Russia.
Valentina KiselevaDepartment of Radiation Biochemistry, A. Tsyb Medical Radiological Research Center-Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Korolev str.-4, 249036 Obninsk, Russia.
Liana MkrtchyanDepartment of Radiation and Combined Treatment of Gynecological Diseases, A. Tsyb Medical Radiological Research Center, Korolev str.-4, 249036 Obninsk, Russia.
Ludmila KrikunovaDepartment of Radiation and Combined Treatment of Gynecological Diseases, A. Tsyb Medical Radiological Research Center, Korolev str.-4, 249036 Obninsk, Russia.
Ministry of Health of the Russian Federation · RUMedical Radiological Research Center · RU

Funding

Russian Science Foundation 18-75-10025
6 · The paper itself

Abstract

Radio- and chemoresistance of cancer stem cells (CSCs) is considered as one of the possible causes of adverse results of chemoradiotherapy for various malignancies, including cervical cancer. However, little is known about quantitative changes in the CSC subpopulation in the course of treatment and mechanisms for individual response of CSCs to therapy. The purpose of the study was to evaluate the association of radiation response of cervical CSCs with clinical and morphological parameters of disease and features of human papillomavirus (HPV) infection. The proportion of CD44

Indexed as

AlphapapillomavirusAdultAgedCarcinoma, Squamous CellCD24 AntigenDNA, ViralDrug Resistance, NeoplasmFemaleFlow CytometryHumansHyaluronan ReceptorsMiddle AgedNeoplastic Stem CellsPapillomavirus InfectionsPrognosisReal-Time Polymerase Chain ReactionCD24 AntigenCD24 protein, humanCD44 protein, humanDNA, ViralHyaluronan Receptorscancer stem cellscervical cancerflow cytometryhuman papillomavirusradiotherapy

Identifiers

PMID33535561
PMCPMC7867083
OpenAlexW3127223993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.