Evidence map›Paper›PMID 33535486›Full record

ReviewViruses2021

Application of Advanced Light Microscopy to the Study of HIV and Its Interactions with the Host.

Saveez Saffarian

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Saveez SaffarianCenter for Cell and Genome Science, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0002-9186-1230
University of Utah · US

Funding

Dynamics of Gag-Pol auto-processing and ESCRT recruitment during HIV buddingR01AI150474 · NIAID · UNIVERSITY OF UTAH · PI SAFFARIAN, SAVEEZ · 2019 to 2021
$974k
NIAID NIH HHS R01 AI150474
6 · The paper itself

Abstract

This review highlights the significant observations of human immunodeficiency virus (HIV) assembly, release and maturation made possible with advanced light microscopy techniques. The advances in technology which now enables these light microscopy measurements are discussed with special emphasis on live imaging approaches including Total Internal Reflection Fluorescence (TIRF), high-resolution light microscopy techniques including PALM and STORM and single molecule measurements, including Fluorescence Resonance Energy Transfer (FRET). The review concludes with a discussion on what new insights and understanding can be expected from these measurements.

Indexed as

Host-Pathogen InteractionsFluorescence Resonance Energy TransferHIV-1HIV InfectionsHumansMicroscopyMicroscopy, FluorescenceSingle Molecule ImagingVirus AssemblyVirus ReleaseVirus ReplicationESCRTsGagHIViPALMPALMSTEDSTORMTIRF

Identifiers

PMID33535486
PMCPMC7912744
OpenAlexW3127738630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.