Evidence map›Paper›PMID 33535448›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Complexes of Copper and Iron with Pyridoxamine, Ascorbic Acid, and a Model Amadori Compound: Exploring Pyridoxamine's Secondary Antioxidant Activity.

Guillermo García-Díez, Roger Monreal-Corona, Nelaine Mora-Diez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Feasibility of controlled nitric oxide generationDalton transactions (Cambridge, England : 2003) · 2025
    Article
  2. Article
  3. Article
  4. Revisiting the HORoyal Society open science · 2023
    Article
  5. Pyridoxamine treatment ameliorates large artery stiffening and cerebral artery endothelial dysfunction in old mice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guillermo García-DíezDepartment of Chemistry, Thompson Rivers University, Kamloops, BC V2C 0C8, Canada.
Roger Monreal-CoronaDepartment of Chemistry, Thompson Rivers University, Kamloops, BC V2C 0C8, Canada.ORCID 0000-0003-3071-9887
Nelaine Mora-DiezDepartment of Chemistry, Thompson Rivers University, Kamloops, BC V2C 0C8, Canada.ORCID 0000-0002-1648-2222

Funding

Natural Sciences and Engineering Research Council of Canada Discovery Grant
6 · The paper itself

Abstract

The thermodynamic stability of 11 complexes of Cu(II) and 26 complexes of Fe(III) is studied, comprising the ligands pyridoxamine (PM), ascorbic acid (ASC), and a model Amadori compound (AMD). In addition, the secondary antioxidant activity of PM is analyzed when chelating both Cu(II) and Fe(III), relative to the rate constant of the first step of the Haber-Weiss cycle, in the presence of the superoxide radical anion (O2•-) or ascorbate (ASC

Indexed as

Amadori compoundsaminoguanidineascorbatecopper complexesglycation inhibitorHaber–Weiss cycleiron complexesMarcus theorypyridoxaminesuperoxide radical anion

Identifiers

PMID33535448
PMCPMC7912584

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.