Evidence map›Paper›PMID 33535247›Full record

ArticleEuropean journal of dentistry2021

Final Endodontic Irrigation with 2% Peracetic Acid: Antimicrobial Activity and Cytotoxicity.

Daniel de Oliveira Brandão-Neto, João Victor Zebende Mello, Marilia Fagury Videira Marceliano-Alves, Thais Machado de Carvalho Coutinho, Eduardo Fagury Videira Marceliano, Michelle Paiva Weydt Galhardi, Vívian Souza Tavares, Aline Peçanha Muzy Dias, Renata Ximenes Lins

Open access · hybridAbstract read
In one paragraph

Article in European journal of dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Daniel de Oliveira Brandão-NetoPostgraduate Program in Dentistry, Health Institute of Nova Friburgo, Fluminense Federal University, Nova Friburgo, Rio de Janeiro, Brazil.
João Victor Zebende MelloSchool of Dentistry, Health Institute of Nova Friburgo, Fluminense Federal University, Nova Friburgo, Rio de Janeiro, Brazil.
Marilia Fagury Videira Marceliano-AlvesPost Graduation Program in Dentistry and Research, Iguaçu University, Nova Iguaçu, Rio de Janeiro, Brazil.
Thais Machado de Carvalho CoutinhoPost Graduation Program in Dentistry and Research, Iguaçu University, Nova Iguaçu, Rio de Janeiro, Brazil.
Eduardo Fagury Videira MarcelianoDental Clinic Department, Brazilian Army General Hospital of Belem, Belem, Brazil.
Michelle Paiva Weydt GalhardiDepartment of Dental Materials, Sao Jose University, Rio de Janeiro, Brazil.
Vívian Souza TavaresSchool of Dentistry, Health Institute of Nova Friburgo, Fluminense Federal University, Nova Friburgo, Rio de Janeiro, Brazil.
Aline Peçanha Muzy DiasSchool of Dentistry, Health Institute of Nova Friburgo, Fluminense Federal University, Nova Friburgo, Rio de Janeiro, Brazil.
Renata Ximenes LinsPostgraduate Program in Dentistry, Health Institute of Nova Friburgo, Fluminense Federal University, Nova Friburgo, Rio de Janeiro, Brazil.
Universidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of present study was to assess the cytotoxicity and antimicrobial efficacy of 2% peracetic acid (PAA) compared with 5.25% sodium hypochlorite (NaOCl) and 2% chlorhexidine (CHX). MATERIAL AND

methodsFor the cytotoxicity test, 100 µl of the tested solutions were added in 12 wells with ECV 304 endothelial cells in each group: NaOCl, CHX, and PAA, in addition to the control group. Each solution was evaluated after 24 hours of contact in four dilutions: 0.2, 0.1, 0.05 and 0.025 through mitochondrial function using MTT colorimetric assay. In the antimicrobial evaluation, 40 dentin blocks 5 mm in length and 0.2 g in weight were incubated with 400 µl of STATISTICAL ANALYSIS: The results obtained were expressed as mean (A570 nm) ± standard deviation (SD) and in a multiple linear regression model and multiple comparisons conducted.

resultsThe antimicrobial evaluation revealed that the NaOCl and CHX groups showed a statistically significant difference compared with the control group (

Identifiers

PMID33535247
PMCPMC8382456
OpenAlexW3128260269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.