Evidence map›Paper›PMID 33535074›Full record

ArticleInternational journal of cardiology2021

Quality assurance of quantitative cardiac T1-mapping in multicenter clinical trials - A T1 phantom program from the hypertrophic cardiomyopathy registry (HCMR) study.

Qiang Zhang, Konrad Werys, Iulia A Popescu, Luca Biasiolli, Ntobeko A B Ntusi, Milind Desai, Stefan L Zimmerman, Dipan J Shah, Kyle Autry, Bette Kim and 40 more

Abstract readMulticenter Study
In one paragraph

Article in International journal of cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
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  8. Cardiovascular magnetic resonance for evaluation of cardiac involvement in COVID-19: recommendations by the Society for Cardiovascular Magnetic Resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Review
  9. Imaging Methods: Magnetic Resonance Imaging.Circulation. Cardiovascular imaging · 2023
    Review
  10. Fast, interleaved, Look-Locker-based TNMR in biomedicine · 2023
    Article
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  18. Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: protocol design of COVID-HEART-a UK, multicentre, observational study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  19. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

50 authors.

Qiang ZhangOxford Centre for Clinical Magnetic Resonance Research, Oxford BRC NIHR, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK. Electronic address: qiang.zhang@cardiov.ox.ac.uk.
Konrad WerysOxford Centre for Clinical Magnetic Resonance Research, Oxford BRC NIHR, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK.
Iulia A PopescuOxford Centre for Clinical Magnetic Resonance Research, Oxford BRC NIHR, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK.
Luca BiasiolliOxford Centre for Clinical Magnetic Resonance Research, Oxford BRC NIHR, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK.
Ntobeko A B NtusiDepartment of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Milind DesaiCleveland Clinic, USA.
Stefan L ZimmermanJohns Hopkins Hospital, USA.
Dipan J ShahHouston Methodist DeBakey Heart & Vascular Center, USA.
Kyle AutryHouston Methodist DeBakey Heart & Vascular Center, USA.
Bette KimMount Sinai West Hospital; Icahn School of Medicine at Mount Sinai, USA.
Han W KimDuke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, USA.
Elizabeth R JenistaDuke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, USA.
Steffen HuberDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, USA.
James A WhiteStephenson Cardiac Imaging Centre, Libin Cardiovascular Institute, University of Calgary, Canada.
Gerry P McCannDepartment of cardiovascular sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, UK.
Saidi A MohiddinInherited Cardiovascular Diseases, Barts Heart Centre, London, UK.
Redha BoubertakhBarts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, UK.
Amedeo ChiribiriKing's College London and Guy's and St Thomas' NHS Foundation Trust, UK.
David NewbyCentre for Cardiovascular Science, University of Edinburgh, UK.
Sanjay PrasadNational Heart and Lung Institute, Imperial College and Royal Brompton Hospital, London, UK.
Aleksandra RadjenovicInstitute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
Dana DawsonAberdeen Cardiovascular and Diabetes Centre, College of Life Sciences and Medicine, University of Aberdeen, UK.
Jeanette Schulz-MengerCharité, University Medicine Berlin ECRC and Helios Clinics, Berlin, Germany.
Heiko MahrholdtDepartment of Cardiology, Robert Bosch Medical Center, Stuttgart, Germany.
Iacopo CarboneDepartment of Radiological, Oncological and Pathological Sciences, Sapienza, University of Rome, Italy.
Ornella RimoldiUniversita' Vita Salute San Raffaele, Milan, Italy.
Stefano ColagrandeDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Italy.
Linda CalistriDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Italy.
Michelle MichelsErasmus MC, department of cardiology, Rotterdam, the Netherlands.
Mark B M Hofmandept. Radiology and Nuclear Medicine, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.
Lisa AndersonCardiology Clinical Academic Group, St George's University of London, UK.
Craig BrobergKnight Cardiovascular Institute, Oregon Health and Science University, USA.
Flett AndrewUniversity Hospital Southampton NHS Trust, UK.
Javier SanzMount Sinai Hospital, New York, NY, USA.
Chiara Bucciarelli-DucciUniversity of Bristol, UK.
Kelvin ChowSiemens Medical Solutions USA, Inc., Chicago, IL, USA.
David HigginsPhilips Electronics UK Limited, Surrey, UK.
David A BroadbentBiomedical Imaging Sciences Department, University of Leeds, Leeds, UK.
Scott SempleEdinburgh Imaging, Centre for Cardiovascular Science, University of Edinburgh, UK.
Tarik HafyaneMontreal Heart Institute, Canada.
Joanne WormleightonUniversity Hospitals of Leicester NHS Trust, UK.
Michael SalernoUniversity of Virginia, USA.
Taigang HeThe Cardiology Clinical Academic Group (CAG), St George's University of London, St George's University Hospitals NHS Foundation Trust, UK.
Sven PleinDepartment of Biomedical Imaging Science, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, UK.
Raymond Y KwongCardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, USA.
Michael Jerosch-HeroldBrigham and Women's Hospital, USA.
Christopher M KramerUniversity of Virginia Health, USA.
Stefan NeubauerOxford Centre for Clinical Magnetic Resonance Research, Oxford BRC NIHR, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK.
Vanessa M FerreiraOxford Centre for Clinical Magnetic Resonance Research, Oxford BRC NIHR, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK.
Stefan K PiechnikOxford Centre for Clinical Magnetic Resonance Research, Oxford BRC NIHR, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK.

Funding

HCMR Novel Markers of Prognosis in Hypertrophic CardiomyopathyU01HL117006 · NHLBI · UNIVERSITY OF VIRGINIA · PI KRAMER, CHRISTOPHER M., NEUBAUER, STEFAN · 2013 to 2017
$14.5M
British Heart Foundation PG/15/71/31731Medical Research Council MR/N003403/1NHLBI NIH HHS U01 HL117006
6 · The paper itself

Abstract

backgroundQuantitative cardiovascular magnetic resonance T1-mapping is increasingly used for myocardial tissue characterization. However, the lack of standardization limits direct comparability between centers and wider roll-out for clinical use or trials. PURPOSE: To develop a quality assurance (QA) program assuring standardized T1 measurements for clinical use.

methodsMR phantoms manufactured in 2013 were distributed, including ShMOLLI T1-mapping and reference T1 and T2 protocols. We first studied the T1 and T2 dependency on temperature and phantom aging using phantom datasets from a single site over 4 years. Based on this, we developed a multiparametric QA model, which was then applied to 78 scans from 28 other multi-national sites.

resultsT1 temperature sensitivity followed a second-order polynomial to baseline T1 values (R

conclusionsThe proposed phantom QA for T1-mapping can assure correct method implementation and protocol adherence, and is robust to temperature variation and phantom aging. This QA program circumvents the need of frequent phantom replacements, and can be readily deployed in multicenter trials.

Indexed as

Cardiomyopathy, HypertrophicMagnetic Resonance ImagingHumansPhantoms, ImagingRegistriesReproducibility of ResultsCardiac MRIMulticenter studyPhantom studyQuality assuranceQuantitative T1-mappingStandardization

Identifiers

PMID33535074
PMCPMC7994017

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.