ArticleAmerican journal of respiratory and critical care medicine2021
Characteristics and Mechanisms of a Sphingolipid-associated Childhood Asthma Endotype.
Open access · greenAbstract readComparative Study
In one paragraph
Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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47citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
What it found
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Who cites it
47 citing papers in PubMed, 57 citations in OpenAlex.
- Trial
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- Metabolomic Approaches to Lung Function in Pediatric Asthma: A Narrative Review.Children (Basel, Switzerland) · 2026Review
- The ratio of circulatory levels of sphingolipids to steroids predicts asthma exacerbations.Nature communications · 2026Article
- From gut microbiota dysbiosis to immune dysregulation: pathogenic mechanisms and emerging therapeutic perspectives in pediatric asthma.Frontiers in immunology · 2026Review
- Establishing an untargeted lipidomics workflow for cellular analysis: insights into endothelial cell function in anaphylaxis.Frontiers in immunology · 2026Article
- Multi-omics to study chronic respiratory diseases and viral infections.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Association of Childhood Asthma with the Concept of Exposomics: A Short Review.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Biomarker Discovery in Childhood Asthma: A Pilot Study of Serum Metabolite Analysis for IgE-Dependent Allergy.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- [Lipid analysis in children with bronchial asthma based on liquid chromatography-mass spectrometry: a prospective study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Metabolomics in Childhood Asthma - a Promising Tool to Meet Various Clinical Needs.Current allergy and asthma reports · 2025Review
- Effects of azithromycin on alleviating airway inflammation in asthmatic mice by regulating airway microbiota and metabolites.Microbiology spectrum · 2025Article
- The Microbiome in Asthma Heterogeneity: The Role of Multi-Omic Investigations.Immunological reviews · 2025Review
- Pharmacokinetic modeling of prenatal vitamin D exposure and the impact on offspring asthma and pulmonary function.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025Article
- Improvement of glucocorticoid sensitivity and attenuation of pulmonary allergic reactions by exogenous supplementation with betaine in HDM and LPS-induced allergic mouse model.Clinical and translational allergy · 2025Article
- Plasma lipids, amino acids, and their metabolic pathways as potential biomarkers for differential diagnosis of cold and heat syndrome asthma in children: a preliminary study.Frontiers in pediatrics · 2025Article
- Phytotherapeutic BS012 and Its Active Component Ameliorate Allergic Asthma via Inhibition of Th2-Mediated Immune Response and Apoptosis.Biomolecules & therapeutics · 2024Article
- Metabolomic profiles during early childhood and risk of food allergies and asthma in multiethnic children from a prospective birth cohort.The Journal of allergy and clinical immunology · 2024Article
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Authors and funding
18 authors at 5 institutions in 3 countries.
Daniela RagoCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
Casper-Emil T PedersenCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
Mengna HuangChanning Division of Network Medicine, Brigham and Women's Hospital-Harvard Medical School, Harvard University, Boston, Massachusetts.
Rachel S KellyChanning Division of Network Medicine, Brigham and Women's Hospital-Harvard Medical School, Harvard University, Boston, Massachusetts.ORCID 0000-0003-3023-1822
Gözde GürdenizCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
Nicklas BrustadCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
Hanna KnihtiläChanning Division of Network Medicine, Brigham and Women's Hospital-Harvard Medical School, Harvard University, Boston, Massachusetts.
Kathleen A Lee-SarwarChanning Division of Network Medicine, Brigham and Women's Hospital-Harvard Medical School, Harvard University, Boston, Massachusetts.
Andréanne MorinDepartment of Human Genetics, University of Chicago, Chicago, Illinois.
Morten A RasmussenCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
Jakob StokholmCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
Klaus BønnelykkeCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
Augusto A LitonjuaDivision of Pediatric Pulmonary Medicine, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; and.
Craig E WheelockDivision of Physiological Chemistry II, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.ORCID 0000-0002-8113-0653
Scott T WeissChanning Division of Network Medicine, Brigham and Women's Hospital-Harvard Medical School, Harvard University, Boston, Massachusetts.
Jessica Lasky-SuChanning Division of Network Medicine, Brigham and Women's Hospital-Harvard Medical School, Harvard University, Boston, Massachusetts.
Hans BisgaardCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
Bo L ChawesCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital-University of Copenhagen, Gentofte, Denmark.
University of Copenhagen · DKBrigham and Women's Hospital · USKarolinska Institutet · SEUniversity of Chicago · USUniversity of Rochester Medical Center · US
Funding
VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8MMulti-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthmaUH3OD023268 · OD · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2018 to 2022
$13.5MSystems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2016 to 2020
$12.6MStatistical GeneticsP01HL083069 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2007 to 2011
$12.2MIntegrative Metabolomics of Asthma SeverityR01HL123915 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LASKY-SU, JESSICA A · 2014 to 2023
$7.0MOmic Determinants of Longitudinal Lung Function in AsthmaR01HL155742 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LASKY-SU, JESSICA A, MCGEACHIE, MICHAEL JOHN · 2021 to 2025
$3.9MMechanistic insights into asthma pathogenesis through the integration of asthma genes, risk exposures, and metabolomicsR01HL141826 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LASKY-SU, JESSICA A · 2018 to 2021
$3.4MPrenatal Origins of AsthmaR01HL129735 · NHLBI · UNIVERSITY OF CHICAGO · PI BISGAARD, HANS, OBER, CAROLE · 2015 to 2018
$3.2MMulti-Omic Endotyping of AsthmaK01HL146980 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KELLY, RACHEL SABINE · 2019 to 2023
$891kMulti-Omics Analysis of the Association of Polyunsaturated Fatty Acids with Asthma and Allergy in ChildhoodK08HL148178 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LEE-SARWAR, KATHLEEN A · 2019 to 2022
$683kNHLBI NIH HHS K01 HL146980NHLBI NIH HHS K08 HL148178NHLBI NIH HHS P01 HL083069NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R01 HL123915NHLBI NIH HHS R01 HL129735NHLBI NIH HHS R01 HL141826NHLBI NIH HHS R01 HL155742NIEHS NIH HHS P30 ES001247NIH HHS UH3 OD023268
Abstract
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Indexed as
Age FactorsAsthmaChildCohort StudiesDNA ReplicationFemaleGene Expression RegulationGenetic VariationGenotypeHumansInfantMalePhenotypeProspective StudiesRespiratory Function TestsRisk FactorsSphingolipidschildhood asthmalung functionsphingolipids
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.