Evidence map›Paper›PMID 33534647›Full record

Observational studyJCO oncology practice2021

Racial, Ethnic, and Socioeconomic Discrepancies in Opioid Prescriptions Among Older Patients With Cancer.

Lucas K Vitzthum, Vinit Nalawade, Paul Riviere, Whitney Sumner, Tyler Nelson, Loren K Mell, Timothy Furnish, Brent Rose, María Elena Martínez, James D Murphy

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in JCO oncology practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Opioid conversion in adults with cancer: MASCC-ASCO-AAHPM-HPNA-NICSO guideline.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Shared decision making in routine oncology appointments with Black patients with lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Pharmacogenetics: Using science to reduce racial bias in pain management?Journal of the American Geriatrics Society · 2023
    Article
  20. Racial and Ethnic Disparities in Opioid Access and Urine Drug Screening Among Older Patients With Poor-Prognosis Cancer Near the End of Life.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lucas K VitzthumDepartment of Radiation Oncology, Stanford University, Stanford, CA.ORCID 0000-0003-2033-6874
Vinit NalawadeDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.ORCID 0000-0002-6594-6740
Paul RiviereDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.
Whitney SumnerDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.
Tyler NelsonDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.ORCID 0000-0001-5216-7337
Loren K MellDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.ORCID 0000-0003-2277-6080
Timothy FurnishDivision of Pain Management, Department of Anesthesiology, University of California San Diego, La Jolla, CA.
Brent RoseDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.
María Elena MartínezDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA.ORCID 0000-0002-6728-1834
James D MurphyDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.ORCID 0000-0002-0523-9091
University of California San Diego · USStanford University · US

Funding

Research Education CoreU54CA132384 · NCI · SAN DIEGO STATE UNIVERSITY · PI CRIPPS, RICHARD MATTHEW, CROWE, SHEILA E. · 2008 to 2022
$20.7M
Research Education CoreU54CA132379 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ARREDONDO, ELVA M, CROWE, SHEILA E. · 2008 to 2021
$16.1M
Quantification and Characterization of Opioid Prescription, Overdose, and Fatalities in People with Cancer: A Massive Nationwide, Multi-Cohort StudyR03DA053541 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MURPHY, JAMES D · 2021 to 2022
$158k
NCI NIH HHS U54 CA132379NCI NIH HHS U54 CA132384NIDA NIH HHS R03 DA053541
6 · The paper itself

Abstract

purposeMinority race and lower socioeconomic status are associated with lower rates of opioid prescription and undertreatment of pain in multiple noncancer healthcare settings. It is not known whether these differences in opioid prescribing exist among patients undergoing cancer treatment. METHODS AND MATERIALS: This observational cohort study involved 33,872 opioid-naive patients of age > 65 years undergoing definitive cancer treatment. We compared rates of new opioid prescriptions by race or ethnicity and socioeconomic status controlling for differences in baseline patient, cancer, and treatment factors. To evaluate downstream impacts of opioid prescribing and pain management, we also compared rates of persistent opioid use and pain-related emergency department (ED) visits.

resultsCompared with non-Hispanic White patients, the covariate-adjusted odds of receiving an opioid prescription were 24.9% (95% CI, 16.0 to 33.9,

conclusionFor older patients with cancer, rates of opioid prescriptions and pain-related outcomes significantly differed by race and area-level poverty. Non-Hispanic Black patients were associated with a significantly decreased likelihood of receiving an opioid prescription. Patients from high-poverty areas were more likely to develop persistent opioid use and have a pain-related ED visit.

Indexed as

Analgesics, OpioidNeoplasmsAgedEthnicityHumansPractice Patterns, Physicians'PrescriptionsSocial ClassAnalgesics, Opioid

Identifiers

PMID33534647
PMCPMC8258011
OpenAlexW3128439938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.