Evidence map›Paper›PMID 33534032›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021

The measurement performance of the EQ-5D-5L versus EQ-5D-3L in patients with hidradenitis suppurativa.

Alex Bató, Valentin Brodszky, L Hunor Gergely, Krisztián Gáspár, Norbert Wikonkál, Ágnes Kinyó, Ákos Szabó, Zsuzsanna Beretzky, Andrea Szegedi, Éva Remenyik and 3 more

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Psychometric properties of four FACE-Q Aesthetics scales in patients planning and undergoing minimally invasive facial cosmetic procedures.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  3. Is EQ-5D-5L better than EQ-5D-3L? A comparison of descriptive systems and utility scores in patients with kidney chronic disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  4. Comparing the measurement properties of the EQ-5D-Y-3L and EQ-5D-3L in a general population sample of adults.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  5. Qualitative testing of the EQ-HWB-9 with a 'blank' EQ-HWB VAS and EQ-5D-5L with skin bolt-ons in a rare genetic skin disease population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  6. Article
  7. Comparing EQ-5D-5L, PROPr, SF-6D and TTO utilities in patients with chronic skin diseases.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  8. Article
  9. Measurement properties of the EQ-5D-3L, EQ-5D-5L, and SF-6Dv2 in patients with late-onset Pompe disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Article
  10. Population-level norm values by EQ-5D-3L in Hungary - a comparison of survey results from 2022 with those from 2000.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  11. Article
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  14. Article
  15. Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L descriptive systems and utilities in atopic dermatitis.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  16. Comparison of EQ-5D-3L and 5L versions following operative fixation of closed ankle fractures.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  17. Measurement properties of the ICECAP-A capability well-being instrument among dermatological patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alex BatóDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8, H-1093, Budapest, Hungary.ORCID http://orcid.org/0000-0002-1450-4790
Valentin BrodszkyDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8, H-1093, Budapest, Hungary. valentin.brodszky@uni-corvinus.hu.ORCID http://orcid.org/0000-0002-6095-2295
L Hunor GergelyDepartment of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Mária u. 41, H-1085, Budapest, Hungary.ORCID http://orcid.org/0000-0001-5266-4667
Krisztián GáspárFaculty of Medicine, Departments of Dermatology, University of Debrecen, Nagyerdei krt. 98, H-4032, Debrecen, Hungary.ORCID http://orcid.org/0000-0001-6530-7052
Norbert WikonkálDepartment of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Mária u. 41, H-1085, Budapest, Hungary.ORCID http://orcid.org/0000-0003-4949-8711
Ágnes KinyóUniversity of Pécs Medical School Department of Dermatology, Venereology and Oncodermatology, Akác utca 1, H-7632, Pécs, Hungary.
Ákos SzabóDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8, H-1093, Budapest, Hungary.ORCID http://orcid.org/0000-0003-2386-4525
Zsuzsanna BeretzkyDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8, H-1093, Budapest, Hungary.
Andrea SzegediFaculty of Medicine, Departments of Dermatology, University of Debrecen, Nagyerdei krt. 98, H-4032, Debrecen, Hungary.ORCID http://orcid.org/0000-0003-2109-9014
Éva RemenyikFaculty of Medicine, Departments of Dermatology, University of Debrecen, Nagyerdei krt. 98, H-4032, Debrecen, Hungary.ORCID http://orcid.org/0000-0002-0973-5228
Norbert KissDepartment of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Mária u. 41, H-1085, Budapest, Hungary.ORCID http://orcid.org/0000-0002-9947-1755
Miklós SárdyDepartment of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, Mária u. 41, H-1085, Budapest, Hungary.ORCID http://orcid.org/0000-0003-4306-5093
Fanni RenczDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8, H-1093, Budapest, Hungary.ORCID http://orcid.org/0000-0001-9674-620X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHidradenitis suppurativa (HS) is a chronic inflammatory skin disease that affects up to 1% of the population in Europe. The EQ-5D is the most commonly used generic instrument for measuring health-related quality of life among HS patients. This study aims to compare the measurement properties of the two adult versions of EQ-5D (EQ-5D-3L and EQ-5D-5L) in patients with HS.

methodsWe recruited 200 consecutive patients with HS (mean age 37 years, 38% severe or very severe HS) to participate in a multicentre cross-sectional survey. Patients completed the EQ-5D-3L, EQ-5D-5L, Dermatology Life Quality Index (DLQI) and Skindex-16 questionnaires.

resultsMore than twice as many different health state profiles occurred in the EQ-5D-5L compared to the EQ-5D-3L (101 vs. 43). A significant reduction in ceiling effect was found for the mobility, self-care and usual activities dimensions. A good agreement was established between the EQ-5D-3L and EQ-5D-5L with an intraclass correlation coefficient of 0.872 (95% CI 0.830-0.903; p < 0.001) that was confirmed by a Bland-Altman plot. EQ-5D-5L improved both the absolute and relative informativity in all dimensions except for anxiety/depression. EQ-5D-3L and EQ-5D-5L demonstrated similar convergent validity with DLQI and Skindex-16. EQ-5D-5L was able to better discriminate between known groups of patients based on the number of comorbidities and disease severity (HS-Physician's Global Assessment).

conclusionIn patients with HS, the EQ-5D-5L outperformed the EQ-5D-3L in feasibility, ceiling effects, informativity and known-groups validity for many important clinical characteristics. We recommend using the EQ-5D-5L in HS patients across various settings, including clinical care, research and economic evaluations.

Indexed as

AdultFemaleHidradenitis SuppurativaHumansMalePsychometricsQuality of LifeEQ-5D-3LEQ-5D-5LHealth-related quality of lifeHidradenitis suppurativaPsychometricsValidity

Identifiers

PMID33534032
PMCPMC8068690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.