ArticleNeuroradiology2021
Peritumoral brain edema volume in meningioma correlates with tumor fractional anisotropy but not apparent diffusion coefficient or cerebral blood volume.
Article in Neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Fractional anisotropy, perfusion, and metabolic correlates of peritumoural brain oedema in meningiomas: a cross-sectional observational multiparametric MRI study.BMC medical imaging · 2026Observational
- Topological feature-driven TabPFN model for prediction of enlarged hemorrhage and edema after tumor resection in meningiomas.Frontiers in medicine · 2026Article
- Predicting intraoperative meningioma consistency using features from standard MRI sequences: a preoperative evaluation.Acta neurochirurgica · 2025Article
- Glymphatic system impairment in sleep disruption: diffusion tensor image analysis along the perivascular space (DTI-ALPS).Japanese journal of radiology · 2023Article
- Glymphatic system impairment in corticobasal syndrome: diffusion tensor image analysis along the perivascular space (DTI-ALPS).Japanese journal of radiology · 2023Article
- Multisite harmonization of diffusion tensor image analysis along the perivascular space using the COMBined Association Test.Japanese journal of radiology · 2023Article
- Reproducibility of automated calculation technique for diffusion tensor image analysis along the perivascular space.Japanese journal of radiology · 2023Article
- Reproducibility of diffusion tensor image analysis along the perivascular space (DTI-ALPS) for evaluating interstitial fluid diffusivity and glymphatic function: CHanges in Alps index on Multiple conditiON acquIsition eXperiment (CHAMONIX) study.Japanese journal of radiology · 2022Article
- Glymphatic Dysfunction in Patients With Ischemic Stroke.Frontiers in aging neuroscience · 2021Article
- Peritumoral Brain Edema in Metastases May Be Related to Glymphatic Dysfunction.Frontiers in oncology · 2021Article
- Peritumoral Brain Edema in Meningiomas May Be Related to Glymphatic Dysfunction.Frontiers in neuroscience · 2021Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
purposePathogenesis of peritumoral brain edema (PTBE) in meningiomas remains unclear. Associations between PTBE volume and diffusion or perfusion properties of meningioma have not been studied. We aimed to investigate if diffusion and perfusion properties of meningioma correlate with its PTBE volume.
methodsSeventy consecutive patients (mean age, 58.9 ± 13.7 years; 37 women) with meningiomas who had preoperative DTI and DSC-PWI were retrospectively analyzed. PTBE volume, tumor volume, and mean T2 signal, ADC, FA, and CBV of the tumor were measured. Between meningiomas with and without PTBE, patient age and sex, as well as T2 signal intensity, volume, ADC, FA, and CBV of tumors, were compared. In meningiomas with PTBE, correlations of PTBE volume with patient age and sex, as well as T2 signal intensity, volume, ADC, FA, and CBV of tumors, were analyzed. Multivariable linear regression analysis was performed to identify factors associated with PTBE volume.
resultsOn univariable analysis, meningiomas without PTBE were more frequently found in women (P = 0.033) and demonstrated lower ADC (P = 0.020), higher FA (P < 0.001), and lower CBV (P < 0.001). PTBE volume of meningiomas correlated with tumor ADC (r = 0.444; P = 0.001), tumor FA (r = - 0.655; P < 0.001), and tumor CBV (r = 0.402; P = 0.003). On multivariable analysis, tumor FA was the only factor associated with PTBE volume (P < 0.001).
conclusionPTBE volume in meningioma correlates with tumor FA. DTI may help to understand the mechanism of PTBE in meningiomas.
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