Evidence map›Paper›PMID 33533738›Full record

ArticleAsian journal of andrology

Complications and management of penile augmentation with hyaluronic acid injection.

Yuan Quan, Zi-Rui Gao, Xiang Dai, Ling Kuang, Min Zhang, Qing Li, Tao Xu, Xiao-Wei Zhang

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Penile Volume Augmentation With Hyaluronic Acid Fillers: Ultrasound Observation.Plastic and reconstructive surgery. Global open · 2025
    Article
  5. Complications and management of penile enhancement procedures.Translational andrology and urology · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Penile girth enhancement procedures for aesthetic purposes.International journal of impotence research · 2022
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yuan QuanDepartment of Urology, Peking University People's Hospital, Beijing 100044, China.
Zi-Rui GaoDepartment of Dermatology and Venereology, Peking University People's Hospital, Beijing 100044, China.
Xiang DaiDepartment of Urology, Peking University People's Hospital, Beijing 100044, China.
Ling KuangDepartment of Nephrology Division, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
Min ZhangDepartment of Urology, Chengdu Kowloon Hospital, Chengdu 614000, China.
Qing LiDepartment of Urology, Peking University People's Hospital, Beijing 100044, China.
Tao XuDepartment of Urology, Peking University People's Hospital, Beijing 100044, China.
Xiao-Wei ZhangDepartment of Urology, Peking University People's Hospital, Beijing 100044, China.
Peking University · CNSichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyaluronic acid injection is becoming a popular way for penile augmentation. However, only few studies and follow-ups have investigated the various complications of hyaluronic acid injection and their corresponding management. In this study, a total of 230 patients who had penile augmentation with hyaluronic acid injection from January 2018 to December 2019 were examined on follow-up for penile girth, complications, and their corresponding management. At 1-month, 3-month, and 6-month postoperative follow-ups, the penile circumference had increased by 2.66 ± 1.24 cm, 2.28 ± 1.02 cm, and 1.80 ± 0.83 cm, respectively. During the entire 6-month follow-up, 4.3% had complications such as subcutaneous bleeding, subcutaneous nodules, and infection. There were no systemic or local allergic reactions among all the patients. All complications were treated accordingly, and no further deterioration or severe sequelae were observed. Although complications of hyaluronic acid injections are mild and rare, these may affect the patient's satisfaction postoperatively. Preoperative redundant prepuce may increase the incidence of penile edema or postoperative gel migration. Standardization of the surgery protocol and elucidation of the effects of other injection parameters are still lacking. Nevertheless, it still highlights the importance of preoperative preparation and surgical technique.

Indexed as

Patient SatisfactionAdultAftercareChinaHumansHyaluronic AcidInjectionsMaleMiddle AgedPenisPostoperative ComplicationsHyaluronic Acidcomplicationshyaluronic acid injectionpenile augmentation

Identifiers

PMID33533738
PMCPMC8269832
OpenAlexW3129127464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.