Evidence map›Paper›PMID 33533737›Full record

ArticleAsian journal of andrology

A novel robust nomogram based on peripheral monocyte counts for predicting lymph node metastasis of prostate cancer.

Jia-Wei Zhou, Yun-Hua Mao, Yang Liu, Hai-Tao Liang, Chandni Chandur Samtani, Yue-Wu Fu, Yun-Lin Ye, Gang Xiao, Zi-Ke Qin, Cun-Dong Liu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Jia-Wei ZhouDepartment of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Yun-Hua MaoDepartment of Urology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
Yang LiuDepartment of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Hai-Tao LiangDepartment of Urology, Cancer Center of Sun Yat-sen University, Guangzhou 510060, China.
Chandni Chandur SamtaniDepartment of International Medical Education, The Southern Medical University, Guangzhou 510515, China.
Yue-Wu FuDepartment of Surgery, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Yun-Lin YeDepartment of Urology, Cancer Center of Sun Yat-sen University, Guangzhou 510060, China.
Gang XiaoDepartment of Laboratory Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Zi-Ke QinDepartment of Urology, Cancer Center of Sun Yat-sen University, Guangzhou 510060, China.
Cun-Dong LiuDepartment of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Jian-Kun YangDepartment of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Qi-Zhao ZhouDepartment of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Wen-Bin GuoDepartment of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Kang-Yi XueDepartment of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Shan-Chao ZhaoDepartment of Urology, Nanfang Hospital of Southern Medical University, Guangzhou 510515, China.
Ming-Kun ChenDepartment of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Third Affiliated Hospital of Southern Medical University · CNSouthern Medical University · CNSun Yat-sen University · CNFirst Affiliated Hospital of Jinan University · CNSun Yat-sen University Cancer Center · CNThird Affiliated Hospital of Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate methods for identifying pelvic lymph node metastasis (LNM) of prostate cancer (PCa) prior to surgery are still lacking. We aimed to investigate the predictive value of peripheral monocyte count (PMC) for LNM of PCa in this study. Two hundred and ninety-eight patients from three centers were divided into a training set (n = 125) and a validation set (n = 173). In the training set, the independent predictors of LNM were analyzed using univariate and multivariate logistic regression analyses, and the optimal cutoff value was calculated by the receiver operating characteristic (ROC) curve. The sensitivity and specificity of the optimal cutoff were authenticated in the validation cohort. Finally, a nomogram based on the PMC was constructed for predicting LNM. Multivariate analyses of the training cohort demonstrated that clinical T stage, preoperative Gleason score, and PMC were independent risk factors for LNM. The subsequent ROC analysis showed that the optimal cutoff value of PMC for diagnosing LNM was 0.405 × 109 l

Indexed as

NomogramsAgedAged, 80 and overChinaHumansLogistic ModelsLymphatic MetastasisLymph NodesMaleMiddle AgedMonocytesProstatectomyProstatic NeoplasmsIymph node metastasismagnetic resonance imagingmonocytenomogramprostate cancer

Identifiers

PMID33533737
PMCPMC8269827
OpenAlexW3125975004

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.