ArticleDeutsches Arzteblatt international2020
Long-Term Survival Following Sepsis.
Article in Deutsches Arzteblatt international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Perspective on Lessons Not Learned: From Coley's Toxins to Microbial Drug Delivery, Guidance for Institutional Review Boards (IRBs).International journal of molecular sciences · 2026Review
- Long-term survival in patients discharged alive from hospital following an intensive care unit admission with sepsis or septic shock in Australia and New Zealand: an observational cohort study.The Lancet regional health. Western Pacific · 2026Article
- The impact of community-acquired critical sepsis on long-term mortality and morbidity-a nationwide cohort study.Scientific reports · 2026Article
- [Sepsis care in Germany: quality indicators on diagnostics and treatment of sepsis].Die Anaesthesiologie · 2026Article
- Integrating bioinformatics and machine learning to discover sumoylation associated signatures in sepsis.Scientific reports · 2025Article
- Biomarkers Affecting Treatment Outcomes of Febrile Neutropenia in Hematological Patients with Lymphomas: Is Presepsin the New Promising Diagnostic and Prognostic Biomarker?Journal of clinical medicine · 2025Article
- Systolic Pulmonary Artery Pressure as Long-Term Mortality Predictor in Elderly Critically Ill with Severe COVID-19 Pneumonia.Viruses · 2025Article
- Two-Year Mortality and Prognostic Factors in Sepsis: A Prospective Cohort Study of 714 Danish Emergency Department Patients.Clinical epidemiology · 2025Article
- Evaluating optimal rehabilitation strategies in ICU: study protocol for a multicentre cohort study to assess Physical Activity dosing, Muscle mass, and physICal outcomeS (IPAMICS study).Annals of clinical epidemiology · 2024Article
- Urgent call for attention to diabetes-associated hospital infections.World journal of diabetes · 2024Article
- A dynamic nomogram for predicting 28-day mortality in septic shock: a Chinese retrospective cohort study.PeerJ · 2024Article
- One-year survival after admission in the intensive care unit: a retrospective cohort study.Revista da Associacao Medica Brasileira (1992) · 2024Observational
- A comprehensive analysis of immune features and construction of an immune gene diagnostic model for sepsis.BMC genomics · 2023Article
- Characteristics and outcomes of sepsis patients with and without COVID-19.Journal of infection and public health · 2022Article
- Article
- [Sepsis-associated deaths in Germany: characteristics and regional variation].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022Article
- Critical Parameters in Dynamic Network Modeling of Sepsis.Frontiers in network physiology · 2022Article
- Blood Sugar Targets in Surgical Intensive Care—Management and Special Considerations in Patients With DiabetesDeutsches Arzteblatt international · 2021Review
- [Methodological weaknesses and errors in the data extraction lead to a substantial underestimation of the mortality of sepsis and septic shock in Germany].Der Anaesthesist · 2021Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere have not yet been any prospective registry studies in Germany with active investigation of the long-term survival of patients with sepsis.
methodsThe Jena Sepsis Registry (JSR) included all patients with a diagnosis of sepsis in the four intensive care units of Jena University Hospital from January 2011 to December 2015. Long-term survival 6-48 months after diagnosis was documented by asking the treating general practitioners. The survival times were studied with Kaplan-Meier estimators. Cox regressions were calculated to show associations between possible predictors and survival time.
results1975 patients with sepsis or septic shock were included. The mean time of observation was 730 days. For 96.4% of the queries to the general practitioners, information on long-term survival was available. Mortality in the intensive care unit was 34% (95% confidence interval [32; 37]), and in-hospital mortality was 45% [42; 47]. The overall mortality six months after diagnosis was 59% [57; 62], the overall mortality 48 months after diagnosis was 74% [72; 78]. Predictors of shorter survival were age, nosocomial origin of sepsis, diabetes, cerebrovascular disease, duration of stay in the intensive care unit, and renal replacement therapy.
conclusionThe nearly 75% mortality four years after diagnosis indicates that changes are needed both in the acute treatment of patients with sepsis and in their multi-sector long-term care. The applicability of these findings may be limited by their having been obtained in a single center.
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