Evidence map›Paper›PMID 33533553›Full record

ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2021

Position statement for a pragmatic approach to immunotherapeutics in patients with inflammatory skin diseases during the coronavirus disease 2019 pandemic and beyond.

J Beecker, K A Papp, J Dutz, R B Vender, R Gniadecki, C Cooper, P Gisondi, M Gooderham, C H Hong, M G Kirchhof and 4 more

Open access · bronzeAbstract readConsensus Statement
In one paragraph

Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 3 countries.

J BeeckerUniversity of Ottawa, Ottawa, ON, Canada.ORCID https://orcid.org/0000-0003-0872-3388
K A PappProbity Medical Research Inc., Waterloo, ON, Canada.ORCID https://orcid.org/0000-0001-9557-3642
J DutzSkin Care Center, Vancouver, BC, Canada.
R B VenderDermatrials Research Inc., Hamilton, ON, Canada.ORCID https://orcid.org/0000-0002-2624-2724
R GniadeckiProbity Medical Research Inc., Waterloo, ON, Canada.ORCID https://orcid.org/0000-0002-2310-8300
C CooperUniversity of Ottawa, Ottawa, ON, Canada.ORCID https://orcid.org/0000-0002-3368-3499
P GisondiDepartment of Medicine, Section of Dermatology and Venereology, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0002-1777-9001
M GooderhamProbity Medical Research Inc., Waterloo, ON, Canada.ORCID https://orcid.org/0000-0001-8926-0113
C H HongProbity Medical Research Inc., Waterloo, ON, Canada.
M G KirchhofUniversity of Ottawa, Ottawa, ON, Canada.
C W LyndeProbity Medical Research Inc., Waterloo, ON, Canada.
C MaariInnovaderm Research Inc, Montreal, QC, Canada.
Y PoulinCentre de Recherche Dermatologique du Québec Métropolitain, Québec, QC, Canada.
L PuigDepartment of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.ORCID https://orcid.org/0000-0001-6083-0952
University of Ottawa · CAUniversity of British Columbia · CADermatrials Research · CAHospital de Sant Pau · ESHôtel-Dieu de Québec · CAInnovaderm (Canada) · CALynde Centre for Dermatology · CAProbity Medical Research · CASKiN Health · CAUniversity of Alberta · CAUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, a novel RNA virus that was declared a global pandemic on 11 March 2020. The efficiency of infection with SARS-CoV-2 is reflected by its rapid global spread. The SARS-CoV-2 pandemic has implications for patients with inflammatory skin diseases on systemic immunotherapy who may be at increased risk of infection or more severe infection. This position paper is a focused examination of current evidence considering the mechanisms of action of immunotherapeutic drugs in relation to immune response to SARS-CoV-2. We aim to provide practical guidance for dermatologists managing patients with inflammatory skin conditions on systemic therapies during the current pandemic and beyond. Considering the limited and rapidly evolving evidence, mechanisms of action of therapies, and current knowledge of SARS-CoV-2 infection, we propose that systemic immunotherapy can be continued, with special considerations for at risk patients or those presenting with symptoms.

Indexed as

ImmunotherapyCOVID-19DermatitisHumansPractice Patterns, Physicians'Risk Assessment

Identifiers

PMID33533553
PMCPMC8014810
OpenAlexW3127185312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.