ArticleJournal of gastroenterology and hepatology2021
Dynamic diagnosis of early gastric cancer with microvascular blood flow rate using magnifying endoscopy (with video): A pilot study.
Article in Journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Establishment and Prospective Validation of a Classification System for Surface Microvessels in Peritoneal Lesions Under Magnifying Endoscopy.Diagnostics (Basel, Switzerland) · 2026Article
- Usefulness of Automated Analysis System for Microvascular Blood Flow Rate Using Magnifying Endoscopy in Early Gastric Cancer: A Multicenter Retrospective Study (With Video).Journal of gastroenterology and hepatology · 2025Article
- Mucin phenotype and microvessels in early gastic cancer: Magnifying endoscopy with narrow band imaging.Heliyon · 2024Article
- Novel physiological analysis using blood flow velocity for colonic polyps: Pilot study.Endoscopy international open · 2024Article
- In Vivo Anchoring Bis-Pyrene Probe for Molecular Imaging of Early Gastric Cancer by Endoscopic Techniques.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Dynamic diagnosis of early gastric cancer with microvascular blood flow rate using magnifying endoscopy (with video): A pilot study.Journal of gastroenterology and hepatology · 2021Article
- Mechanisms ofIntegrative cancer therapiesReview
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimMagnifying endoscopy (ME) diagnostic algorithm for early gastric cancer (EGC) relies on qualitative features such as microvascular (MV) architecture and microsurface structure; however, it is a "static" diagnostic algorithm that uses still images. ME can visualize red blood cell flow within subepithelial microvessels in real time. Here, we evaluated the utility of using the MV blood flow rate in combination with ME for the diagnosis of EGC as a retrospective study.
methodsPatients with differentiated-type EGC (n = 10) or patchy redness (n = 10) underwent ME with blue laser imaging. The mean MV blood flow rates of EGC, patchy redness, and background mucosa were calculated by the mean movement distance of one tagging red blood cell using split images of ME with blue laser imaging videos. We compared the mean MV blood flow rate between EGC, patchy redness, and background mucosa and also calculated the MV blood flow imaging ratio (inside lesion/background mucosa) between EGC and patchy redness.
resultsMean MV blood flow rate was significantly lower in EGC (1481 μm/s; range 1057-1762) than in patchy redness (3859 μm/s; 2435-5899) or background mucosa (4140.6 μm/s; 2820-6247) (P < 0.01). The MV blood flow imaging ratio was significantly lower in EGC (0.39; 0.27-0.62) than in patchy redness (0.90; 0.78-1.1) (P < 0.01).
conclusionsDynamic diagnosis with MV blood flow rate using ME may be useful for the differential diagnosis of EGC and patchy redness. Endoscopic assessment of dynamic processes within the gastric mucosa may facilitate the diagnosis of EGC.
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