ArticleSchizophrenia bulletin2021
A Network of Psychopathological, Cognitive, and Motor Symptoms in Schizophrenia Spectrum Disorders.
Article in Schizophrenia bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Exploring interrelationships between cognition, functioning and quality of life in schizophrenia spectrum disorders: a Bayesian analysis of networks.European archives of psychiatry and clinical neuroscience · 2026Article
- Unraveling the complex relationships between anxiety, depression, and quality of life in schizophrenia: a network analysis study.European archives of psychiatry and clinical neuroscience · 2026Article
- Longitudinal measurements of inhibitory cognitive performance in patients with schizophrenia and bipolar disorder.Schizophrenia research. Cognition · 2026Article
- Living with psychosis and cognitive impairment: a qualitative study.BMC psychiatry · 2026Article
- Exploring the Interactions Between Psychotic Symptoms, Cognition, and Environmental Risk Factors: A Bayesian Analysis of Networks.Schizophrenia bulletin · 2025Article
- The network approach to psychopathology: investigating inter-individual variability and the association with clinical relapse in psychosis.Schizophrenia (Heidelberg, Germany) · 2025Article
- Predictive role of exteroceptive and interoceptive bodily dimensions to schizotypal personality traits.Scientific reports · 2025Article
- Associations of Vocal Features, Psychiatric Symptoms, and Cognitive Functions in Schizophrenia.Neuropsychiatric disease and treatment · 2025Article
- The role of prefrontal-hippocampal functional connectivity in schizophrenia-related cognitive dysfunction and the thalamic ventral midline involvement:Frontiers in neuroscience · 2025Review
- Construction and Brain Validation of circRNAs-miRNAs-mRNAs Regulatory Axis in Early-Onset Schizophrenia.Neuropsychiatric disease and treatment · 2025Article
- Cognitive Impairments Related to COMT and Neuregulin 1 Phenotypes as Transdiagnostic Markers in Schizophrenia Spectrum Patients.Journal of clinical medicine · 2024Article
- The dimensional structure of the Positive and Negative Syndrome Scale in first-episode schizophrenia spectrum disorders: an Exploratory Graph Analysis from the OPTiMiSE trial.Schizophrenia (Heidelberg, Germany) · 2024Article
- Functional magnetic resonance imaging in schizophrenia: current evidence, methodological advances, limitations and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Is cognition integral to psychopathology? A population-based cohort study.Psychological medicine · 2023Article
- Structure-function coupling in white matter uncovers the abnormal brain connectivity in Schizophrenia.Translational psychiatry · 2023Article
- Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment.Molecular psychiatry · 2023Review
- Violent behavior and the network properties of psychopathological symptoms and real-life functioning in patients with schizophrenia.Frontiers in psychiatry · 2023Article
- The Important Role of Motivation and Pleasure Deficits on Social Functioning in Patients With Schizophrenia: A Network Analysis.Schizophrenia bulletin · 2022Article
- Clinical Consequences of Motor Behavior as Transdiagnostic Phenomenon.Schizophrenia bulletin · 2022Article
- The Puzzle of Functional Recovery in Schizophrenia-Spectrum Disorders-Replicating a Network Analysis Study.Schizophrenia bulletin · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Schizophrenia spectrum disorders (SSDs) are complex syndromes involving psychopathological, cognitive, and also motor symptoms as core features. A better understanding of how these symptoms mutually impact each other could translate into diagnostic, prognostic, and, eventually, treatment advancements. The present study aimed to: (1) estimate a network model of psychopathological, cognitive, and motor symptoms in SSD; (2) detect communities and explore the connectivity and relative importance of variables within the network; and (3) explore differences in subsample networks according to remission status. A sample of 1007 patients from a multisite cohort study was included in the analysis. We estimated a network of 43 nodes, including all the items from the Positive and Negative Syndrome Scale, a cognitive assessment battery and clinical ratings of extrapyramidal symptoms. Methodologies specific to network analysis were employed to address the study's aims. The estimated network for the total sample was densely interconnected and organized into 7 communities. Nodes related to insight, abstraction capacity, attention, and suspiciousness were the main bridges between network communities. The estimated network for the subgroup of patients in remission showed a sparser density and a different structure compared to the network of nonremitted patients. In conclusion, the present study conveys a detailed characterization of the interrelations between a set of core clinical elements of SSD. These results provide potential novel clues for clinical assessment and intervention.
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