Evidence map›Paper›PMID 33533316›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2021

Chitinase 3-like-1 protects airway function despite promoting type 2 inflammation during fungal-associated allergic airway inflammation.

Joseph J Mackel, Jaleesa M Garth, MaryJane Jones, Diandra A Ellis, Jonathan P Blackburn, Zhihong Yu, Sadis Matalon, Miranda Curtiss, Frances E Lund, Annette T Hastie and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Fungal chitin is not an independent mediator of allergic fungal asthma severity.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  5. Hematopoietic 12/15-lipoxygenase activity negatively contributes to fungal-associated allergic asthma.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  6. Article
  7. Chitinase-3-like 1 regulates TFrontiers in immunology · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Joseph J MackelDepartment of Medicine, University of Alabama Birmingham, Birmingham, Alabama.
Jaleesa M GarthDepartment of Medicine, University of Alabama Birmingham, Birmingham, Alabama.
MaryJane JonesDepartment of Microbiology and Immunology, Tulane University, New Orleans, Louisiana.
Diandra A EllisDepartment of Microbiology and Immunology, Tulane University, New Orleans, Louisiana.
Jonathan P BlackburnDepartment of Medicine, University of Alabama Birmingham, Birmingham, Alabama.
Zhihong YuDepartment of Medicine, University of Alabama Birmingham, Birmingham, Alabama.
Sadis MatalonDepartment of Medicine, University of Alabama Birmingham, Birmingham, Alabama.
Miranda CurtissDepartment of Medicine, University of Alabama Birmingham, Birmingham, Alabama.
Frances E LundDepartment of Microbiology, University of Alabama Birmingham, Birmingham, Alabama.
Annette T HastieDepartment of Medicine, Wake Forest University, Winston-Salem, North Carolina.ORCID 0000-0001-6607-7797
Deborah A MeyersDepartment of Medicine, University of Arizona, Tucson, Arizona.
Chad SteeleDepartment of Microbiology and Immunology, Tulane University, New Orleans, Louisiana.
University of Alabama at Birmingham · USTulane University · USUniversity of Arizona · USWake Forest University · US

Funding

Immunopathogenesis in fungal asthmaR01HL122426 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Chad Steele · 2015 to 2026
$5.1M
Bromine Inhalation Induced Lung Injury: Novel Mechanisms and Treatment StrategiesU01ES026458 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MATALON, SADIS · 2015 to 2019
$3.9M
Biology of innate IL-22 during lung fungal infectionR01HL136211 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STEELE, CHAD · 2017 to 2024
$3.0M
Mitigation of Chlorine Injury to MitochondriaR21ES032956 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MATALON, SADIS · 2021 to 2022
$422k
NHLBI NIH HHS R01 HL122426NHLBI NIH HHS R01 HL136211NIEHS NIH HHS R21 ES032956NIEHS NIH HHS U01 ES026458
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAspergillosisAspergillus fumigatusChitinase-3-Like Protein 1FemaleInflammationMaleMiceMice, Inbred BALB CMice, KnockoutRespiratory HypersensitivityChil1 protein, mouseChitinase-3-Like Protein 1asthmafungalinflammation

Identifiers

PMID33533316
PMCPMC8238152
OpenAlexW3127712836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.