Evidence map›Paper›PMID 33533112›Full record

ArticleThe international journal of medical robotics + computer assisted surgery : MRCAS2021

Magnetic resonance image-guided focused ultrasound robotic system for transrectal prostate cancer therapy.

Marinos Giannakou, Theocharis Drakos, Georgios Menikou, Nikolas Evripidou, Antria Filippou, Kyriakos Spanoudes, Leonidas Ioannou, Christakis Damianou

Open access · hybridAbstract read
In one paragraph

Article in The international journal of medical robotics + computer assisted surgery : MRCAS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Towards Design and Development of an MRI Conditional Robot to Enable Curvilinear Transperineal Prostate Biopsy.The international journal of medical robotics + computer assisted surgery : MRCAS · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Preclinical robotic device for magnetic resonance imaging guided focussed ultrasound.The international journal of medical robotics + computer assisted surgery : MRCAS · 2023
    Article
  7. Robotic device for transcranial focussed ultrasound applications in small animal models.The international journal of medical robotics + computer assisted surgery : MRCAS · 2022
    Article
  8. Article
  9. Review
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Marinos GiannakouR&D, Medsonic LTD, Limassol, Cyprus.ORCID https://orcid.org/0000-0002-6777-0515
Theocharis DrakosR&D, Medsonic LTD, Limassol, Cyprus.
Georgios MenikouElectrical Engineering Department, Cyprus University of Technology, Limassol, Cyprus.
Nikolas EvripidouElectrical Engineering Department, Cyprus University of Technology, Limassol, Cyprus.
Antria FilippouElectrical Engineering Department, Cyprus University of Technology, Limassol, Cyprus.
Kyriakos SpanoudesElectrical Engineering Department, Cyprus University of Technology, Limassol, Cyprus.ORCID https://orcid.org/0000-0001-9484-7920
Leonidas IoannouRadiology Department, Ygia Polyclinic, Limassol, Cyprus.
Christakis DamianouElectrical Engineering Department, Cyprus University of Technology, Limassol, Cyprus.ORCID https://orcid.org/0000-0003-0424-2851
Cyprus University of Technology · CYMedsonic (Cyprus) · CYPolyclinic Medical Center · US

Funding

Research & Innovation Foundation of Cyprus ENTERPRISES/0918/0012
6 · The paper itself

Abstract

backgroundA magnetic resonance image (MRI) guided robotic device for focussed ultrasound therapy of prostate cancer (PC) was developed. The device offers movement in 5 degrees of freedom (DOF) and uses a single-element transducer that operates at 3.2 MHz, has a diameter of 25 mm and focuses at 45 mm.

methodsThe MRI compatibility of the system was evaluated in a 1.5 T scanner. The ability of the transducer to create lesions was evaluated in laboratory and MRI settings, on ex vivo pork tissue and in vivo rabbit thigh tissue.

resultsCavitational and thermal lesions were created on the excised pork tissue. In vivo experiments proved the efficacy of the system in ablating muscle tissue without damaging intervening areas.

conclusionsThe MRI compatible robotic system can be placed on the table of any commercial MRI scanner up to 7 T. The device has the ability of future use for transrectal focal therapy of PC with the patient in supine position.

Indexed as

Prostatic NeoplasmsRobotic Surgical ProceduresAnimalsHumansMagnetic Resonance ImagingMaleRabbitsUltrasonographyfocused ultrasoundMRgFUSMRIprostaterobotic device

Identifiers

PMID33533112
PMCPMC8244034
OpenAlexW3129130094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.