Evidence map›Paper›PMID 33533107›Full record

SynthesisPhytotherapy research : PTR2021

Oral application of Chinese herbal medicine for allergic rhinitis: A systematic review and meta-analysis of randomized controlled trials.

Hong Li, Jenny Manuela Kreiner, Ann Rann Wong, Mingdi Li, Yue Sun, Leyao Lu, Jianping Liu, Angela Wei Hong Yang

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Phytotherapy research : PTR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. New progress in pediatric allergic rhinitis.Frontiers in immunology · 2024
    Review
  8. Article
  9. Pharmaceutics · 2023
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hong LiSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia.ORCID https://orcid.org/0000-0002-3874-4860
Jenny Manuela KreinerSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia.ORCID https://orcid.org/0000-0002-1739-0661
Ann Rann WongSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia.ORCID https://orcid.org/0000-0003-1391-180X
Mingdi LiSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia.ORCID https://orcid.org/0000-0002-5329-4562
Yue SunSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia.ORCID https://orcid.org/0000-0002-0807-9847
Leyao LuSchool of Life Sciences, Guangzhou University, Guangzhou, China.ORCID https://orcid.org/0000-0002-1853-951X
Jianping LiuCentre for Evidence-based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-0320-061X
Angela Wei Hong YangSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia.ORCID https://orcid.org/0000-0001-9345-4607
RMIT University · AUBeijing University of Chinese Medicine · CNGuangzhou University · CN

Funding

Cochrane Complementary Medicine Field: Resource for ResearchR24AT001293 · NCCIH · UNIVERSITY OF MARYLAND BALTIMORE · PI BERMAN, BRIAN M, WIELAND, LISA SUSAN · 2003 to 2022
$9.4M
NCCIH NIH HHS R24 AT001293RMIT Emerging Researcher Grant
6 · The paper itself

Abstract

Chinese herbal medicine (CHM) has long been used for allergic rhinitis (AR). This systematic review aimed to investigate the clinical effects and safety of oral CHM for AR by comparing it to Western medications (WM). Nineteen databases were searched up to May 27, 2020. Randomized controlled trials (RCTs) assessing the effects of CHM on the primary or secondary outcomes comparing to WM, in any age of the patients, were included. The pooled results were expressed as mean difference, standardized mean difference, or odds ratio with 95% confidence intervals. Eighteen RCTs were included and 17 of them were evaluated in the meta-analysis. CHM may improve total nasal symptom scores, individual symptom scores (rhinorrhea, nasal congestion, sneezing, and nasal itching), quality of life, and recurrence rate, compared to antihistamines (loratadine and chlorpheniramine). Only mild and transient adverse events of CHM were reported. However, there were no significant differences in some subgroup analyses in total nasal symptom scores, rhinorrhea, nasal obstruction, sneezing, nasal itching, and SF-36. Due to the small number of included studies, poor quality of trial design, and substantial heterogeneities, the potential of CHM for AR should be validated in large, multicenter, and well-designed RCTs in the future.

Indexed as

Drugs, Chinese HerbalHumansQuality of LifeRandomized Controlled Trials as TopicRhinitis, AllergicDrugs, Chinese Herbalallergic diseasescomplementary and alternative medicineHay fevernasal symptomsnatural productstraditional Chinese medicine

Identifiers

PMID33533107
PMCPMC8457023
OpenAlexW3127738345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.