Evidence map›Paper›PMID 33533008›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2021

Endometrial Organoids: A Rising Star for Research on Endometrial Development and Associated Diseases.

Yong Song, Asgerally T Fazleabas

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Less is more! Low amount ofFrontiers in immunology · 2024
    Article
  8. Review
  9. The role of organoids in cancer research.Experimental hematology & oncology · 2023
    Review
  10. Review
  11. Article
  12. Review
  13. Strategies for modelling endometrial diseases.Nature reviews. Endocrinology · 2022
    Review
  14. Review
  15. Bovine and human endometrium-derived hydrogels support organoid culture from healthy and cancerous tissues.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yong SongDepartment of Obstetrics, Gynecology and Reproductive Biology, Michigan State University, Grand Rapids, Michigan, 49503, USA.
Asgerally T FazleabasDepartment of Obstetrics, Gynecology and Reproductive Biology, Michigan State University, Grand Rapids, Michigan, 49503, USA. fazleaba@msu.edu.ORCID 0000-0001-6139-5067

Funding

Modulation of the Receptive Endometrium by CGR01HD042280 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FAZLEABAS, ASGERALLY T. · 2003 to 2020
$4.6M
NICHD NIH HHS R01 HD042280
6 · The paper itself

Abstract

The endometrium is one of the most dynamic organs in the human body. Until now, cell lines have furthered the understanding of endometrial biology and associated diseases, but they failed to recapitulate the key physiological aspects of the endometrium, especially as it relates to its complex architecture and functions. Organoid culture systems have become an alternative approach to reproduce biological functions of tissues in vitro. Endometrial organoids have now been established from stem/progenitor cells and/or differentiated cells by several methods, which represents a promising tool to gain a deeper understanding of this dynamic organ. In this review, we will discuss the establishment, characteristics, applications, and potential challenges and directions of endometrial organoids.

Indexed as

EndometriumOrganoidsAnimalsCell Culture Techniques, Three DimensionalCulture TechniquesEmbryo, MammalianEndometrial NeoplasmsEndometriosisExtracellular VesiclesFemaleGonadal Steroid HormonesHumansPolycystic Ovary SyndromePregnancyStem CellsTranscriptomeGonadal Steroid HormonesEndometrial cancerEndometrial developmentEndometrial organoidEndometriosisEndometriumPolycystic ovary syndrome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.