Evidence map›Paper›PMID 33532742›Full record

ArticleSTAR protocols2021

Generation and assessment of high-quality mouse oocytes and embryos following nicotinamide mononucleotide administration.

Yilong Miao, Jingyue Chen, Qian Gao, Bo Xiong

Abstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yilong MiaoCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Jingyue ChenCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Qian GaoCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Bo XiongCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The low quality of oocytes is one of the main causes of the suboptimal reproductive outcome of female mammals with advanced maternal age. Here, we present a detailed protocol to obtain high-quality oocytes and embryos from aged mice by nicotinamide mononucleotide (NMN) administration. We also describe fluorescence staining procedures to assess the organelle dynamics in oocytes, and

Indexed as

AnimalsBlastocystEmbryo Culture TechniquesEmbryonic DevelopmentFemaleFertilization in VitroMiceNicotinamide MononucleotideOocytesNicotinamide MononucleotideCell cultureCell isolationMicroscopy

Identifiers

PMID33532742
PMCPMC7829339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.