Evidence map›Paper›PMID 33532627›Full record

ReviewEndocrinology, diabetes & metabolism2021

Risk factors for Graves' Orbitopathy in surgical patients-Results of a 10-year retrospective study with review of the literature.

Navid Tabriz, Arved Gruben, Verena Uslar, Dirk Weyhe

Open access · goldAbstract readReview
In one paragraph

Review in Endocrinology, diabetes & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Navid TabrizSchool of Medicine and Health Sciences University Hospital for Visceral Surgery Pius-Hospital Oldenburg Carl von Ossietzky University Oldenburg Oldenburg Germany.
Arved GrubenSchool of Medicine and Health Sciences University Hospital for Visceral Surgery Pius-Hospital Oldenburg Carl von Ossietzky University Oldenburg Oldenburg Germany.
Verena UslarSchool of Medicine and Health Sciences University Hospital for Visceral Surgery Pius-Hospital Oldenburg Carl von Ossietzky University Oldenburg Oldenburg Germany.ORCID 0000-0003-3252-2076
Dirk WeyheSchool of Medicine and Health Sciences University Hospital for Visceral Surgery Pius-Hospital Oldenburg Carl von Ossietzky University Oldenburg Oldenburg Germany.
Pius Hospital Oldenburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: We investigated known (eg age, smoking, thyrotropin receptor autoantibody (TRAb)) and new risk factors (eg thyroid peroxidase autoantibodies (TPO-Ab), thyroid size, or BMI) for Graves' disease (GD) and Graves' orbitopathy (GO), especially in combination with each other, to determine which factors play the most important role in the development of GO. Methods: From 2008 to 2018, Results: Age at first diagnosis of GD (OR = 1.043, Conclusion: As it has been shown in univariate analyses, smoking, age and TRAb levels have a negative impact on the onset and course of GD and GO. Via multivariable regression, we could additionally show that smoking is the most important factor out of those analysed. TRAb might be a helpful surrogate parameter in the assessment of the progress of GO and therefore might be one factor in the decision-making process for potential early operative surgery. With regard to the hitherto unclear role of BMI, thyroid size and TPO-Ab in the course of GO, this study could not find any clinically relevant influence.

Indexed as

AdultAge FactorsAutoantibodiesFemaleGraves DiseaseGraves OphthalmopathyHumansMaleMiddle AgedMultivariate AnalysisReceptors, ThyrotropinRetrospective StudiesRisk FactorsSmokingTime FactorsAutoantibodiesReceptors, ThyrotropinGraves' diseasemultivariable analysisthyroid surgeryTRAb

Identifiers

PMID33532627
PMCPMC7831207
OpenAlexW3111185539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.