Evidence map›Paper›PMID 33532604›Full record

SynthesisEndocrinology, diabetes & metabolism2021

Glucose variability and mood in adults with diabetes: A systematic review.

Linda T Muijs, Caterina Racca, Maartje de Wit, Annelies Brouwer, Thomas H Wieringa, Ralph de Vries, Erik H Serné, Daniël H van Raalte, Femke Rutters, Frank J Snoek

Abstract readSystematic Review
In one paragraph

Synthesis in Endocrinology, diabetes & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linda T MuijsMedical Psychology Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0002-5464-8350
Caterina RaccaInternal Medicine Diabetes Center Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0002-3495-0018
Maartje de WitMedical Psychology Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0001-6029-5101
Annelies BrouwerInternal Medicine Diabetes Center Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0001-7195-2840
Thomas H WieringaMedical Psychology Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0001-8440-8844
Ralph de VriesMedical Library Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0002-2075-7495
Erik H SernéInternal Medicine Diabetes Center Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0003-0657-7225
Daniël H van RaalteInternal Medicine Diabetes Center Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0003-2894-6124
Femke RuttersEpidemiology and Biostatistics Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0002-1008-678X
Frank J SnoekMedical Psychology Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.ORCID 0000-0001-9563-6762

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To systematically review the literature regarding the association between glucose variability (GV) and mood in adults with diabetes, appraise the used methods and make suggestions for future research. Methods: A systematic review of literature published up to May 2019 was performed. Abstracts and full texts were screened independently in duplicate. Experimental and observational studies reporting the association between GV and mood in adults with type 1 diabetes or type 2 diabetes were evaluated. A descriptive analysis of the extracted data was conducted, along with a quality assessment. Results: Out of the 2.316 studies screened, eight studies met our criteria. Studies used a variety of measures and metrics to determine GV and mood. Four studies used continuous glucose monitoring (CGM). An association between GV and mood was found in four studies when correlating either postprandial glucose rate of increase with current mood or multiday GV with mood measured retrospectively. The other four studies did not find any association. Conclusions: There is no clear empirical support for a link between GV and mood in adults with type 1 and type 2 diabetes. More rigorous research is warranted using CGM and ecological momentary assessment of mood to assess if and under what conditions an association between GV and mood exists.

Indexed as

AffectBlood GlucoseAdultBiomarkersDiabetes MellitusFemaleHumansMaleMiddle AgedMonitoring, PhysiologicRetrospective StudiesBiomarkersBlood Glucoseadultaffect/moodblood glucose variabilitydiabetes mellitussystematic review

Identifiers

PMID33532604
PMCPMC7831227

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.