Evidence map›Paper›PMID 33532592›Full record

ArticleBioengineering & translational medicine2021

Sonodynamic therapy reduces iron retention of hemorrhagic plaque.

Bicheng Li, Jie Gong, Siqi Sheng, Minqiao Lu, Shuyuan Guo, Jianting Yao, Haiyu Zhang, Xuezhu Zhao, Zhengyu Cao, Xin Sun and 9 more

Abstract read
In one paragraph

Article in Bioengineering & translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. [Utilizing Sonodynamic Therapy-Induced Pyroptosis for Liver Cancer Therapy].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  3. Sonodynamic therapy for the treatment of atherosclerosis.Journal of pharmaceutical analysis · 2024
    Review
  4. Nanomedicine for Diagnosis and Treatment of Atherosclerosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  5. Recent Advances for Dynamic-Based Therapy of Atherosclerosis.International journal of nanomedicine · 2023
    Review
  6. Sonodynamic therapy reduces iron retention of hemorrhagic plaque.Bioengineering & translational medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Bicheng LiDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Jie GongDepartment of Pathophysiology and Key Laboratory of Cardiovascular Pathophysiology Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education Harbin People's Republic of China.
Siqi ShengDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Minqiao LuDepartment of Pathophysiology and Key Laboratory of Cardiovascular Pathophysiology Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education Harbin People's Republic of China.
Shuyuan GuoDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Jianting YaoDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Haiyu ZhangDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Xuezhu ZhaoDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Zhengyu CaoDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Xin SunDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Huan WangDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Yang CaoDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Yongxing JiangDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.
Zhen TianDepartment of Pathophysiology and Key Laboratory of Cardiovascular Pathophysiology Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education Harbin People's Republic of China.
Bin LiuKey Laboratory of Noise and Vibration Research, Institute of Acoustics Chinese Academy of Sciences Beijing People's Republic of China.
Hua ZhaoSchool of Materials and Engineering Harbin Institute of Technology Harbin People's Republic of China.
Zhiguo ZhangSchool of Instrumentation Science and Engineering Harbin Institute of Technology Harbin People's Republic of China.
Hong JinMolecular Vascular Medicine, Medicine Department Karolinska University Hospital Solna Sweden.
Ye TianDepartment of Cardiology, The First Affiliated Hospital, Cardiovascular Institute Harbin Medical University Harbin People's Republic of China.ORCID https://orcid.org/0000-0003-3726-7270

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraplaque hemorrhage (IPH) plays a major role in the aggressive progression of vulnerable plaque, leading to acute cardiovascular events. We previously demonstrated that sonodynamic therapy (SDT) inhibits atherosclerotic plaque progression. In this study, we investigated whether SDT could also be applied to treat more advanced hemorrhagic plaque and addressed the underlying mechanism. SDT decreased atherosclerotic burden, positively altered atherosclerotic lesion composition, and alleviated iron retention in rabbit hemorrhagic plaques. Furthermore, SDT reduced iron retention by stimulating

Indexed as

ferroportin 1intraplaque hemorrhageironmacrophagesonodynamic therapy

Identifiers

PMID33532592
PMCPMC7823128

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.