ArticleBioengineering & translational medicine2021
Point-of-care semen analysis of patients with infertility via smartphone and colorimetric paper-based diagnostic device.
Article in Bioengineering & translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- From Test Offer to Urologic Follow-up: Acceptability of Semen Analysis in Male Infertility and Preconception Care.Cureus · 2026Review
- Nanotechnology in reproductive medicine: from gamete engineering to precision therapeutics.RSC advances · 2026Review
- Machine learning-assisted point-of-care diagnostics for cardiovascular healthcare.Bioengineering & translational medicine · 2025Review
- Diagnostic accuracy of smartphone technology for capturing videos and images of semen analysis samples: A cross-sectional study.Arab journal of urology · 2025Article
- Sustainable Sensing with Paper Microfluidics: Applications in Health, Environment, and Food Safety.Biosensors · 2024Review
- Advancing biological investigations using portable sensors for detection of sensitive samples.Heliyon · 2023Review
- Disposable paper-based microfluidics for fertility testing.iScience · 2022Review
- Development of a Tetrazolium-Derived Paper-Based Diagnostic Device as an Early, Alternative Bacteria Screening Tool.Micromachines · 2021Article
- Detection of Microorganisms in Body Fluids via MTT-PMS Assay.Diagnostics (Basel, Switzerland) · 2021Article
- Small-volume detection: platform developments for clinically-relevant applications.Journal of nanobiotechnology · 2021Review
- Visible colorimetric growth indicators of Neisseria gonorrhoeae for low-cost diagnostic applications.PloS one · 2021Article
- Point-of-care semen analysis of patients with infertility via smartphone and colorimetric paper-based diagnostic device.Bioengineering & translational medicine · 2021Article
- Potential Trends of Point-of-Care Diagnostics-The Next Generation of the Laboratory Diagnosis.Diagnostics (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Male infertility affects millions of males worldwide and is rising in prevalence due to social and environmental conditions. However, men often feel too embarrassed to receive a semen analysis in the hospital due to social stigmas. To overcome this problem, we developed a 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide test strip to distinguish semen samples with low total motile sperm concentration from those with normal motile sperm concentration. This is a point-of-care colorimetric semen analytical method with a one-step, inexpensive, equipment-free evaluation process, and adequate accuracy validated in a 42-sample clinical trial. In this study, results were evaluated visually and with a smartphone application. Using visual observation methods, the area under the curve (AUC) was 0.71 (95% of confidence interval = 0.55-0.86;
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.