Evidence map›Paper›PMID 33532557›Full record

ArticleEndoscopy international open2021

Premedication with simethicone and N-acetylcysteine for improving mucosal visibility during upper gastrointestinal endoscopy in a Western population.

Guido Manfredi, Roberto Bertè, Elena Iiritano, Saverio Alicante, Claudio Londoni, Giancarlo Brambilla, Samanta Romeo, Fernanda Menozzi, Paola Griffanti, Giovanna Brandi and 4 more

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Endoscopy international open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06218537 nacompletednot on this mapstarted 2024, after this paper: background citation

The Role of oAncreatic Enzyme ReplAcement Therapy (PERT) on Mucosal Visibility Before Upper GI Endoscopy

TypeinterventionalSponsorCarol Davila University of Medicine and PharmacyRan2024 to 2024Enrolled42ConditionsUpper Gastrointestinal EndoscopyArmsTest group, Control group
NCT07245095 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Randomized Controlled Trial to Evaluate the Effect of Premedication With N-acetylcysteine and Simethicone on Mucosal Visibility During Elective Upper Gastrointestinal Endoscopy Using the TUGS Score

TypeinterventionalSponsorHospital General de MexicaliRan2025 to 2026Enrolled132ConditionsEsophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, PremedicationArmsPremedication with n-acetylcysteine, Placebo (drinking water), Premedication with simethicone
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Antioxidants (Basel, Switzerland) · 2021
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Guido ManfrediGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Roberto BertèGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Elena IiritanoGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Saverio AlicanteGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Claudio LondoniGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Giancarlo BrambillaGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Samanta RomeoGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Fernanda MenozziGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Paola GriffantiGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Giovanna BrandiGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Oliva MoreschiGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Raffaele PezzilliGastroenterology Department, 'San Carlo' Hospital, Potenza, Italy.
Angelo ZulloGastroenterology, 'Nuovo Regina Margherita' Hospital, Rome, Italy.
Elisabetta BuscariniGastroenterology and Endoscopy Department, ASST Crema Maggiore Hospital, Crema, Italy.
Azienda Ospedaliera Ospedale Maggiore · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITOspedale Regina Margherita · ITOspedale San Carlo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID33532557
PMCPMC7834924
OpenAlexW3124935415

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.