Evidence map›Paper›PMID 33532511›Full record

ArticleACG case reports journal2021

Posterior Reversible Encephalopathy Syndrome After Azathioprine Administration in Severe Ulcerative Colitis.

Filippo Vernia, Mirko Di Ruscio, Arianna Massella, Angela Variola, Renzo Montanari, Paolo Bocus

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Filippo VerniaGastroenterology Unit, Department of Life, Health and Environmental Sciences, University of L'Aquila, Coppito, L'Aquila, Italy.
Mirko Di RuscioGastroenterology Unit, IRCCS Ospedale Sacro Cuore-Don Calabria, Negrar di Valpolicella, Italy.
Arianna MassellaGastroenterology Unit, IRCCS Ospedale Sacro Cuore-Don Calabria, Negrar di Valpolicella, Italy.
Angela VariolaGastroenterology Unit, IRCCS Ospedale Sacro Cuore-Don Calabria, Negrar di Valpolicella, Italy.
Renzo MontanariGastroenterology Unit, IRCCS Ospedale Sacro Cuore-Don Calabria, Negrar di Valpolicella, Italy.
Paolo BocusGastroenterology Unit, IRCCS Ospedale Sacro Cuore-Don Calabria, Negrar di Valpolicella, Italy.
Ospedale Sacro Cuore Don Calabria · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posterior reversible encephalopathy syndrome is a rare syndrome characterized by brain edema and neurological symptoms, often resulting from several drugs. Treatment is based on discontinuation, and diagnosis is thus essential. Only 13 cases of posterior reversible encephalopathy syndrome have been reported in inflammatory bowel diseases, and we present the first after azathioprine in adults. A 56-year-old patient with active ulcerative colitis was found unconscious 5 days after the institution of azathioprine. Right-sided hemiplegia was found after the patient regained consciousness. Magnetic resonance imaging showed altered signal associated with diffusion restriction in the occipital lobe and cerebral vasogenic edema. Complete regression of neurological signs occurred after azathioprine discontinuation.

Identifiers

PMID33532511
PMCPMC7846476
OpenAlexW3127401423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.