Evidence map›Paper›PMID 33532499›Full record

ArticleBioMed research international2021

Acetyl-L-Carnitine Induces Autophagy to Promote Mouse Spermatogonia Cell Recovery after Heat Stress Damage.

Na Qiao, Hanming Chen, Peiquan Du, Zhenlong Kang, Congying Pang, Bingxian Liu, Qiwen Zeng, Jiaqiang Pan, Hui Zhang, Khalid Mehmood and 2 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Role of Melatonin to Ameliorate Oxidative Stress in Sperm Cells.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Na QiaoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.ORCID https://orcid.org/0000-0003-1212-7626
Hanming ChenCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Peiquan DuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Zhenlong KangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Congying PangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Bingxian LiuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Qiwen ZengCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Jiaqiang PanCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Hui ZhangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Khalid MehmoodFaculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.ORCID https://orcid.org/0000-0003-4720-8792
Zhaoxin TangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.ORCID https://orcid.org/0000-0003-4663-0641
Ying LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.ORCID https://orcid.org/0000-0001-5539-0235
South China Agricultural University · CNIslamia University of Bahawalpur · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetyl-L-carnitine (ALC) is an effective substrate for mitochondrial energy metabolism and is known to prevent neurodegeneration and attenuate heavy metal-induced injury. In this study, we investigated the function of ALC in the recovery of mouse spermatogonia cells (GC-1 cells) after heat stress (HS). The cells were randomly divided into three groups: control group, HS group (incubated at 42°C for 90 min), and HS + ALC group (treatment of 150

Indexed as

AcetylcarnitineAnimalsApoptosisAutophagyCell LineHeat-Shock ResponseMaleMalondialdehydeMembrane Potential, MitochondrialMiceOxidative StressSpermatogoniaAcetylcarnitineMalondialdehyde

Identifiers

PMID33532499
PMCPMC7837762
OpenAlexW3125759408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.