Evidence map›Paper›PMID 33532468›Full record

ArticleERJ open research2021

Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis.

Akshay N Gupte, Sriram Selvaraju, Sanjay Gaikwad, Vidya Mave, Pavan Kumar, Subash Babu, Bruno B Andrade, William Checkley, Robert Bollinger, Amita Gupta

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Post-tuberculosis lung disease in treated extra-pulmonary tuberculosis.American journal of respiratory and critical care medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Akshay N GupteDivision of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sriram SelvarajuDept of Clinical Research, National Institute for Research in Tuberculosis, Chennai, India.
Sanjay GaikwadDept of Pulmonary Medicine, Byramjee-Jeejeebhoy Government Medical College, Pune, India.
Vidya MaveDivision of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Pavan KumarNational Institutes of Health - National Institute for Research in Tuberculosis - International Center for Excellence in Research, Chennai, India.
Subash BabuNational Institutes of Health - National Institute for Research in Tuberculosis - International Center for Excellence in Research, Chennai, India.
Bruno B AndradeInstituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador, Brazil.ORCID https://orcid.org/0000-0001-6833-3811
William CheckleyDivision of Pulmonary Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Robert BollingerDivision of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Amita GuptaDivision of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Johns Hopkins University · USInternational Centers for Excellence in Research · INGovernment Medical College · INNational Institute of Research in Tuberculosis · INUniversidade Salvador · BR

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
The Johns Hopkins Baltimore-Washington-India Clinical Trials Unit (BWI CTU)UM1AI069465 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Charles W. Flexner, Amita Gupta · 2012 to 2026
$34.1M
UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
The Impact of Diabetes on TB treatment outcomesR01AI097494 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GOLUB, JONATHAN E. · 2013 to 2017
$3.0M
FIC NIH HHS D43 TW009340NIAID NIH HHS P30 AI094189NIAID NIH HHS R01 AI097494NIAID NIH HHS UM1 AI069465
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID33532468
PMCPMC7836581
OpenAlexW3109412101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.