Evidence map›Paper›PMID 33532463›Full record

ArticleERJ open research2021

Losartan reduces cigarette smoke-induced airway inflammation and mucus hypersecretion.

Michael D Kim, Nathalie Baumlin, John S Dennis, Makoto Yoshida, Adrian Kis, Carolina Aguiar, Andreas Schmid, Eliana Mendes, Matthias Salathe

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  9. Review
  10. E-cigarette aerosols of propylene glycol impair BK channel activity and parameters of mucociliary function.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Michael D KimDept of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Nathalie BaumlinDept of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
John S DennisDept of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Makoto YoshidaDept of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Adrian KisDivision of Pulmonary, Critical Care and Sleep Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Carolina AguiarDept of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Andreas SchmidDept of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Eliana MendesDivision of Pulmonary, Critical Care and Sleep Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Matthias SalatheDept of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.ORCID https://orcid.org/0000-0001-9092-4861
University of Kansas Medical Center · USUniversity of Miami · US

Funding

Anti-inflammatory therapy to augment CFTR rescue in CF patientsR01HL133240 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SALATHE, MATTHIAS A · 2017 to 2020
$2.7M
TRP-mediated airway inflammation by e-cigarette vapingR01HL139365 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SALATHE, MATTHIAS A · 2018 to 2021
$1.8M
NHLBI NIH HHS R01 HL133240NHLBI NIH HHS R01 HL139365
6 · The paper itself

Abstract

The aim was to determine whether losartan reduces cigarette smoke (CS)-induced airway inflammation and mucus hypersecretion in an

Identifiers

PMID33532463
PMCPMC7836504
OpenAlexW3088272386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.