Evidence map›Paper›PMID 33532271›Full record

ArticleQuantitative imaging in medicine and surgery2021

Pulmonary involvement in acquired immunodeficiency syndrome-associated Kaposi's sarcoma: a descriptive analysis of thin-section manifestations in 29 patients.

Chunshuang Guan, Yuxin Shi, Jinxin Liu, Yuxin Yang, Qianqian Zhang, Zhiyan Lu, Guangping Zheng, Wen Ye, Ming Xue, Xingang Zhou and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Kaposi sarcoma with extensive thoracic involvement.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Chunshuang GuanDepartment of Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Yuxin ShiDepartment of Radiology, Shanghai Public Health Clinical Center, Shanghai, China.
Jinxin LiuDepartment of Radiology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Yuxin YangDepartment of Radiology, The Sixth People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China.
Qianqian ZhangDepartment of Radiology, Zhoukou Central Hospital, Zhoukou, China.
Zhiyan LuDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Guangping ZhengDepartment of Radiology, The Shenzhen No. 3 People's Hospital, Guangdong Medical College, Shenzhen, China.
Wen YeDepartment of Radiology, Shanghai Public Health Clinical Center, Shanghai, China.
Ming XueDepartment of Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Xingang ZhouDepartment of Pathology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Na ZhangDepartment of Radiology, Chengdu Public Health Clinical Center, Chengdu, China.
Hongjun LiDepartment of Radiology, Beijing You'an Hospital, Capital Medical University, Beijing, China.
Ruming XieDepartment of Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Budong ChenDepartment of Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Puxuan LuDepartment of Radiology, Shenzhen Center for Chronic Disease Control, Shenzhen, China.
Capital Medical University · CNShanghai Public Health Clinical Center · CNBeijing Ditan Hospital · CNBeijing YouAn Hospital · CNGuangdong Medical College · CNGuangzhou Medical University · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CNPublic Health Clinical Center of Chengdu · CNShenzhen Chronic Disease Prevention Center · CNZhongnan Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcquired immunodeficiency syndrome-associated Kaposi's sarcoma (AIDS-KS) was the first malignant neoplasm to be described as being related to AIDS. The lungs are the most common visceral site of AIDS-KS. This study aimed to analyze the computed tomography (CT) manifestations of pulmonary involvement in AIDS-KS.

methodsTwenty-nine male patients were enrolled in this retrospective study. Imaging evaluation parameters included lesion distribution, the flame sign, interlobular septal thickening, peribronchovascular interstitium thickening, ground-glass opacity (GGO), dilated blood vessels in lesions, and pleural effusion.

resultsA peribronchovascular distribution was observed in all patients, predominantly in the lower lobes. Of the patients, 58.62% (17/29) exhibited the flame sign, 75.86% (22/29) had interlobular septal thickening, 72.41% (21/29) had peribronchovascular interstitium thickening, 82.76% (24/29) had GGO, and 34.48% (10/29) had pleural effusion. Enlarged lymph nodes with a short-axis diameter >1.0 cm were found in 41.38% (12/29) of the patients. Of the 12 patients who underwent contrast-enhanced CT (CECT), 90.91% (11/12) had dilated blood vessels, and nodules, consolidations, and lymph nodes were observed to be strongly enhanced. Intrapulmonary lesions decreased in size or number after appropriate treatment during follow-up.

conclusionsCommon CT manifestations of pulmonary AIDS-KS include the flame sign, peribronchovascular distribution, peribronchovascular interstitium thickening, interlobular septa thickening, GGO, dilated blood vessel, and strong enhancement of nodules, consolidations, and lymph nodes. It is helpful to follow up the therapeutic effect of pulmonary AIDS-KS by chest CT.

Indexed as

Acquired immunodeficiency syndrome (AIDS)Kaposi’s sarcoma (KS)lungspiral computed tomography

Identifiers

PMID33532271
PMCPMC7779939
OpenAlexW3107502955

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.