ArticleQuantitative imaging in medicine and surgery2021
Rapid-kilovoltage-switching dual-energy computed tomography (CT) for differentiating spinal osteolytic metastases from spinal infections.
Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The accuracy of spectral CT with quantitative parameters in differentiating septic from aseptic periprosthetic complications.Insights into imaging · 2026Article
- Diagnosis and Treatment of Skipped Multifocal Spinal Tuberculosis Lesions.Orthopaedic surgery · 2023Review
- Advances in Bone Marrow Imaging: Strengths and Limitations from a Clinical Perspective.Seminars in musculoskeletal radiology · 2023Article
- Physiological iodine uptake of the spine's bone marrow in dual-energy computed tomography - using artificial intelligence to define reference values based on 678 CT examinations of 189 individuals.Frontiers in endocrinology · 2023Article
- Imaging update in spinal tuberculosis.Journal of clinical orthopaedics and trauma · 2022Review
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Abstract
backgroundRapid-kilovoltage-switching dual-energy computed tomography (RDECT) is a non-invasive, alternative technique for quantitative diagnosis. This study aimed to investigate the value of RDECT for differentiating spinal osteolytic metastases (SOM) from spinal infections (SIs).
methodsRDECT was performed on 29 patients with SOM and 18 patients with SIs. Both iodine-based and water-based material decomposition images were generated from the spectral CT scan. The iodine/water densities of lesions on iodine/water material-decomposition images and the CT attenuation values on traditional CT images were measured three times at different image levels, and the averages were calculated. The lesion-to-muscle ratio (LMR) and lesion-to-artery ratio (LAR) for iodine density measurements were calculated. All parameters were compared between the two groups using the two-tailed Student's
resultsIodine density, LMR, and LAR during the arterial phase (AP) and venous phase (VP) were all significantly higher for SOM than for SIs (all P<0.05). The water densities and traditional CT attenuation values during the AP and VP were not significantly different between the two groups. For ROC analysis, LAR during the VP (LAR
conclusionsRDECT can provide additional information that may be useful for differentiating atypical SOM from SIs.
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