Evidence map›Paper›PMID 33532117›Full record

ArticleJournal of the advanced practitioner in oncology2020

Precautions for Patients Taking Aromatase Inhibitors.

Mary Heery, Stephen Farley, Rhett Sparkman, John Healy, William Eighmy, George Zahrah, Richard Zelkowitz

Open access · greenAbstract read
In one paragraph

Article in Journal of the advanced practitioner in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Precautions for Patients Taking Tamoxifen or Aromatase Inhibitors.Journal of the advanced practitioner in oncology · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mary HeeryWestern Connecticut Health Network at The Smilow Family Breast Health Center, Norwalk Hospital, Norwalk, Connecticut.
Stephen FarleyWhittingham Cancer Center, Norwalk Hospital, Norwalk, Connecticut.
Rhett SparkmanWhittingham Cancer Center, Norwalk Hospital, Norwalk, Connecticut.
John HealyWestern Connecticut Health Network at The Smilow Family Breast Health Center, Norwalk Hospital, Norwalk, Connecticut.
William EighmyYale New Haven Hospital, New Haven, Connecticut.
George ZahrahWhittingham Cancer Center, Norwalk Hospital, Norwalk, Connecticut.
Richard ZelkowitzWestern Connecticut Health Network at The Smilow Family Breast Health Center, Norwalk Hospital, Norwalk, Connecticut.
Norwalk Hospital · USYale New Haven Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aromatase inhibitors are the drug of choice for the treatment of estrogen receptor- or progesterone receptor-positive breast cancer in postmenopausal women. Aromatase is an enzyme that catalyzes the final and rate-limiting step in the biosynthesis of estrogen. Inhibitors of this enzyme are an effective therapy for breast cancer. The benefits of these agents have been clearly shown through various clinical trials, yet adherence may be challenging for some patients due to issues of drug interactions, proper first dose education, and adverse effects. Education to prevent and treat adverse effects is of the utmost importance to promote adherence.

Identifiers

PMID33532117
PMCPMC7848814
OpenAlexW3015200070

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.