Trial reportOxidative medicine and cellular longevity2021
A Short-Term Resistance Training Circuit Improved Antioxidants in Sedentary Adults with Down Syndrome.
Trial report in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Physical activity and oxidative stress biomarkers in humans: a systematic review and quantitative meta-analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Effectiveness of Resistance Training in People With Down Syndrome: Systematic Review and Meta-Analysis.Journal of applied research in intellectual disabilities : JARID · 2026Pooled it
- Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression.Annals of medicine · 2025Pooled it
- Circuit training on oxidative stress and arterial health: a health promotion perspective for obese adult men.Frontiers in public health · 2025Trial
- Effects of Resistance Training in Muscle Mass and Markers of Muscle Damage in Adults with Down Syndrome.International journal of environmental research and public health · 2021Trial
- Metabolomic analysis of rat arterial serum under hypobaric hypoxia: Adaptive regulation of physiological systems by metabolic reprogramming.Biochemistry and biophysics reports · 2025Article
- Impact of Resistance Training on Body Composition and Physical Function in Individuals with Down Syndrome: A Meta-Analysis.Diagnostics (Basel, Switzerland) · 2024Review
- Influence of Mediterranean Diet on Sexual Function in People with Metabolic Syndrome: A Narrative Review.Nutrients · 2024Review
- Reference Values of Absolute and Relative Handgrip Strength in Chilean Schoolchildren with Intellectual Disabilities.Children (Basel, Switzerland) · 2022Article
- Resistance training and Down Syndrome: A narrative review on considerations for exercise prescription and safety.Frontiers in physiology · 2022Review
- The Effects of Resistance Training on Physical Fitness and Neuromotor-Cognitive Functions in Adults With Down Syndrome.Frontiers in rehabilitation sciences · 2022Article
- Prescription and Effects of Strength Training in Individuals with Intellectual Disability-A Systematic Review.Sports (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies have found aerobic training improved oxidative damage in people with Down syndrome (DS). However, there is a lack of information regarding the influence of resistance training on redox imbalance in this population. Accordingly, this study was conducted to determine the effect of resistance training (RT) on antioxidant defence system in sedentary adults with DS. Thirty-six male adults with DS were recruited through different community support groups. Eighteen were randomly assigned to perform a circuit RT program with 6 stations, 3 days/week for 12 weeks. Plasma total antioxidant status (TAS), reduced glutathione (GHS), ascorbate, serum
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.