Evidence map›Paper›PMID 33532006›Full record

ArticleDisease markers2021

Characteristics of Three Different Chemiluminescence Assays for Testing for SARS-CoV-2 Antibodies.

Myriam C Weber, Martin Risch, Sarah L Thiel, Kirsten Grossmann, Susanne Nigg, Nadia Wohlwend, Thomas Lung, Dorothea Hillmann, Michael Ritzler, Francesca Ferrara and 14 more

Abstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. The clinical impact of the Covid-19 pandemic first wave on patients with cystic fibrosis in New York.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Myriam C WeberLandesspital Liechtenstein, Heiligkreuz, 9490 Vaduz, Liechtenstein.
Martin RischCentral Laboratory, Kantonsspital Graubünden, Loësstrasse 170, 7000 Chur, Switzerland.ORCID https://orcid.org/0000-0003-4587-5639
Sarah L ThielLandesspital Liechtenstein, Heiligkreuz, 9490 Vaduz, Liechtenstein.
Kirsten GrossmannLabormedizinisches zentrum Dr Risch, Wuhrstrasse 14, 9490 Vaduz, Liechtenstein.
Susanne NiggDepartment of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, Rohrschacherstrasse 95, 9007 St. Gallen, Switzerland.
Nadia WohlwendLabormedizinisches zentrum Dr Risch, Wuhrstrasse 14, 9490 Vaduz, Liechtenstein.
Thomas LungLabormedizinisches zentrum Dr Risch, Wuhrstrasse 14, 9490 Vaduz, Liechtenstein.
Dorothea HillmannLabormedizinisches zentrum Dr Risch, Wuhrstrasse 14, 9490 Vaduz, Liechtenstein.
Michael RitzlerLabormedizinisches zentrum Dr Risch, Wuhrstrasse 14, 9490 Vaduz, Liechtenstein.
Francesca FerraraLabormedizinisches zentrum Dr Risch, Wuhrstrasse 14, 9490 Vaduz, Liechtenstein.
Susanna BiglerLabormedizinisches zentrum Dr Risch, Waldeggstrasse 37, 3097 Liebefeld, Switzerland.
Konrad EgliLabormedizinisches zentrum Dr Risch, Waldeggstrasse 37, 3097 Liebefeld, Switzerland.
Thomas BodmerLabormedizinisches zentrum Dr Risch, Waldeggstrasse 37, 3097 Liebefeld, Switzerland.
Mauro ImperialiCentro medicina di laboratorio Dr Risch, Via Arbostra 2, 6963 Pregassona, Switzerland.
Yacir SalimiClm Dr Risch arc lémanique SA, Chemin de l'Esparcette 10, 1023 Crissier, Switzerland.
Felix FleischDivision of Infectious Diseases, Kantonsspital Graubünden, Loësstrasse 170, 7000 Chur, Switzerland.
Alexia CusiniDivision of Infectious Diseases, Kantonsspital Graubünden, Loësstrasse 170, 7000 Chur, Switzerland.
Sonja HeerBlutspendedienst Graubünden, Loësstrasse 170, 7000 Chur, Switzerland.
Harald RenzInstitute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, University Hospital Giessen and Marburg, Baldingerstraße, 35043 Marburg, Germany.ORCID https://orcid.org/0000-0003-0602-7215
Matthias PaprotnyLandesspital Liechtenstein, Heiligkreuz, 9490 Vaduz, Liechtenstein.
Philipp KohlerDepartment of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, Rohrschacherstrasse 95, 9007 St. Gallen, Switzerland.
Pietro VernazzaDepartment of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, Rohrschacherstrasse 95, 9007 St. Gallen, Switzerland.
Lorenz RischLabormedizinisches zentrum Dr Risch, Wuhrstrasse 14, 9490 Vaduz, Liechtenstein.ORCID https://orcid.org/0000-0003-2692-6699
Christian R KahlertDepartment of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, Rohrschacherstrasse 95, 9007 St. Gallen, Switzerland.ORCID https://orcid.org/0000-0002-0784-3276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several tests based on chemiluminescence immunoassay techniques have become available to test for SARS-CoV-2 antibodies. There is currently insufficient data on serology assay performance beyond 35 days after symptoms onset. We aimed to evaluate SARS-CoV-2 antibody tests on three widely used platforms. A chemiluminescent microparticle immunoassay (CMIA; Abbott Diagnostics, USA), a luminescence immunoassay (LIA; Diasorin, Italy), and an electrochemiluminescence immunoassay (ECLIA; Roche Diagnostics, Switzerland) were investigated. In a multigroup study, sensitivity was assessed in a group of participants with confirmed SARS-CoV-2 (

Indexed as

AdultAntibodies, ViralCOVID-19COVID-19 TestingFemaleHumansLuminescent MeasurementsMaleMiddle AgedPredictive Value of TestsSARS-CoV-2Sensitivity and SpecificityAntibodies, Viral

Identifiers

PMID33532006
PMCPMC7834819

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.