Evidence map›Paper›PMID 33531812›Full record

ArticleTherapeutics and clinical risk management2021

Effects of Scleral Contact Lenses for Keratoconus Management on Visual Quality and Intraocular Pressure.

Martina Formisano, Federica Franzone, Ludovico Alisi, Santino Pistella, Leopoldo Spadea

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. The Impact of Scleral Lenses on Intraocular Pressure.Journal of clinical medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Martina FormisanoEye Clinic, Department of Sense Organs, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy.ORCID 0000-0003-4941-9307
Federica FranzoneEye Clinic, Department of Sense Organs, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy.
Ludovico AlisiEye Clinic, Department of Sense Organs, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy.
Santino PistellaEye Clinic, Department of Sense Organs, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy.
Leopoldo SpadeaEye Clinic, Department of Sense Organs, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy.ORCID 0000-0002-1190-3956
Policlinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the visual acuity level achieved by scleral contact lens (CL) fitting in patients affected by keratoconus and to evaluate possible intraocular pressure (IOP) changes during the scleral CL wear using a transpalpebral tonometer.

methodsIn a prospective case series a comparison was made between visual acuity obtained with glasses, RGP and 16.8mm diameter scleral CL in 30 consecutive patients affected by keratoconus. IOP was tested during scleral CL wear by transpalpebral Diaton Tonometer (DT) and also by Goldmann Applanation Tonometer (GAT) before and after scleral CL wear.

resultsThe mean logMAR visual acuity improved from 0.2±0.25SD with glasses and 0.1±0.02SD with RGP, to -0.002±0.041SD when using the scleral CL (

conclusionScleral CLs remarkably improved visual acuity in keratoconus patients when compared to glasses or RGP contact lenses. Even if it was evidenced a small increase of the mean IOP value during their wear, it may not be significant in otherwise healthy eyes. Statistical analysis demonstrated good agreement between GAT and DT but their numerical values presented a constant gap, that should be taken into account when there is a need to relate the DT values to the reference ones.

Indexed as

higher-order aberrationsIOPkeratoconusscleral contact lens

Identifiers

PMID33531812
PMCPMC7846850
OpenAlexW3124911687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.