ArticleThe ISME journal2021
A mycovirus modulates the endophytic and pathogenic traits of a plant associated fungus.
Article in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 107 citations in OpenAlex.
- A Novel Mycovirus Reprograms the Pathogenic State of Aspergillus flavus in Keratitis.Investigative ophthalmology & visual science · 2026Article
- Microbiome-mediated environmental adaptation in tea plants and its potential applications.Journal of advanced research · 2026Review
- Mycoviruses confer hypovirulence but enhance antifungal volatile organic compound production in a phytopathogenic fungus.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Mycoviruses against plant pathogenic fungi: current understanding and future avenues of their potential implication.Archives of microbiology · 2026Review
- Molecular characterization of a novel hadakavirus from Pestalotiopsis mangiferae.Archives of virology · 2026Article
- A novel partitivirus confers dual contradictory effects to its host fungus: growth attenuation and virulence enhancement.Journal of virology · 2025Article
- A mycovirus enhances fitness of an insect pathogenic fungus and potentially modulates virulence through interactions between viral and host proteins.PLoS pathogens · 2025Article
- Dynamic shifts in plant-microbe relationships.Plant biotechnology (Tokyo, Japan) · 2025Article
- New insights into temperature-impacted mycovirus-fungus interactions regulated by a microRNA inJournal of virology · 2025Article
- Cloning and Characterization of the Mycovirus MpChrV2 fromJournal of fungi (Basel, Switzerland) · 2025Article
- Plasmid-like dynamics of persistent RNA viruses in the host fungal population.Journal of virology · 2025Article
- A hypovirulence-associated capsidless bi-segmented ssRNA mycovirus enhances melanin and microsclerotial production in a vascular phytopathogenic fungus.PLoS pathogens · 2025Article
- High-Throughput Sequencing Reveals the Mycoviral Diversity of the Pathogenic Grape FungusViruses · 2025Article
- Genomic insights reveal community structure and phylogenetic associations of endohyphal bacteria and viruses in fungal endophytes.Environmental microbiome · 2025Article
- Identification of a novelVirusdisease · 2025Article
- A novel tobamo-like mycovirus with filamentous particles replicates in plant cells.Journal of virology · 2025Article
- Mycoviral Diversity ofMicroorganisms · 2025Article
- Molecular and Biological Characterization of an Isolate of Fusarium graminearum dsRNA mycovirus 4 (FgV4) from a New HostMicroorganisms · 2025Article
- Molecular characterization of a novel narnavirus from the plant-pathogenic fungus Ustilaginoidea virens.Archives of virology · 2025Article
- Identification of Mycoviruses inViruses · 2025Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungi are generally thought to live in host plants with a single lifestyle, being parasitism, commensalism, or mutualism. The former, known as phytopathogenic fungi, cause various plant diseases that result in significant losses every year; while the latter, such as endophytic fungi, can confer fitness to the host plants. It is unclear whether biological factors can modulate the parasitic and mutualistic traits of a fungus. In this study, we isolated and characterized a mycovirus from an endophytic strain of the fungus Pestalotiopsis theae, a pathogen of tea (Camellia sinensis). Based on molecular analysis, we tentatively designated the mycovirus as Pestalotiopsis theae chrysovirus-1 (PtCV1), a novel member of the family Chrysoviridae, genus Alphachrysovirus. PtCV1 has four double-stranded (ds) RNAs as its genome, ranging from 0.9 to 3.4 kbp in size, encapsidated in isometric particles. PtCV1 significantly reduced the growth rates of its host fungus in vitro (ANOVA; P-value < 0.001) and abolished its virulence in planta (ANOVA; P-value < 0.001), converting its host fungus to a non-pathogenic endophyte on tea leaves, while PtCV1-free isolates were highly virulent. Moreover, the presence of PtCV1 conferred high resistance to the host plants against the virulent P. theae strains. Here we report a mycovirus that modulates endophytic and phytopathogenic fungal traits and provides an alternative approach to biological control of plant diseases caused by fungi.
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