Evidence map›Paper›PMID 33531394›Full record

ArticlemBio2021

A Trap-Door Mechanism for Zinc Acquisition by

Zhenyao Luo, Jacqueline R Morey, Evelyne Deplazes, Alina Motygullina, Aimee Tan, Katherine Ganio, Stephanie L Neville, Nikolaos Eleftheriadis, Michael Isselstein, Victoria G Pederick and 5 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  6. Hfe Permease andACS infectious diseases · 2024
    Article
  7. Review
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  11. Review
  12. Article
  13. Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake inFrontiers in cellular and infection microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 3 countries.

Zhenyao Luo *School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia.
Jacqueline R Morey *Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
Evelyne DeplazesSchool of Life Sciences, University of Technology Sydney, Ultimo, New South Wales, Australia.ORCID 0000-0003-2052-5536
Alina MotygullinaCentre for Advanced Imaging, The University of Queensland, St. Lucia, Queensland, Australia.
Aimee TanDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-7257-1051
Katherine GanioDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-7360-6466
Stephanie L NevilleDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-7298-9335
Nikolaos EleftheriadisMolecular Microscopy Research Group, Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-1738-6419
Michael IsselsteinPhysical and Synthetic Biology, Faculty of Biology, Ludwig Maximilians-Universität München, Planegg-Martinsried, Germany.
Victoria G PederickDepartment of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
James C PatonResearch Centre for Infectious Diseases, Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0001-9807-5278
Thorben CordesMolecular Microscopy Research Group, Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-8598-5499
Jeffrey R HarmerSchool of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, Bentley, Western Australia, Australia.
Bostjan KobeSchool of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia b.kobe@uq.edu.au christopher.mcdevitt@unimelb.edu.au.ORCID 0000-0001-9413-9166
Christopher A McDevittDepartment of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia b.kobe@uq.edu.au christopher.mcdevitt@unimelb.edu.au.ORCID 0000-0003-1596-4841
The University of Melbourne · AUThe University of Adelaide · AUThe University of Queensland · AUUniversity of Groningen · NLCurtin University · AULudwig-Maximilians-Universität München · DEUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc is an essential element in all domains of life. Nonetheless, how prokaryotes achieve selective acquisition of zinc from the extracellular environment remains poorly understood. Here, we elucidate a novel mechanism for zinc-binding in AdcA, a solute-binding protein of

Indexed as

ATP-Binding Cassette TransportersBacterial ProteinsBinding SitesMolecular Dynamics SimulationProtein ConformationProtein DomainsStreptococcus pneumoniaeZincAdcA protein, StreptococcusATP-Binding Cassette TransportersBacterial ProteinsZincABC transportersolute-binding proteinStreptococcus pneumoniaezinc

Identifiers

PMID33531394
PMCPMC7858048
OpenAlexW3127673963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.