SynthesisDeutsches Arzteblatt international2021
Symptoms During Outpatient Cancer Treatment and Options for Their Management
Synthesis in Deutsches Arzteblatt international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Pooled it
- The effects of art therapy on quality of life and psychosomatic symptoms in adults with cancer: a systematic review and meta-analysis.BMC complementary medicine and therapies · 2023Pooled it
- Four-year follow-up on fatigue and sleep quality of a three-armed partly randomized controlled study in breast cancer survivors with cancer-related fatigue.Scientific reports · 2023Trial
- Incongruent symptom perceptions and its associations with negative mood, intimate relationship and quality of life in colorectal cancer dyads: a dyadic analysis.Journal of patient-reported outcomes · 2026Article
- Influence of socioeconomic status on physical and psychological wellbeing during the cancer care continuum: a longitudinal and logistic regression analysis of cancer patients in New Delhi, India.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Rice Bran Arabinoxylan Compound and Tryptophan Metabolism on Quality of Life of Cancer Patients: A Secondary Analysis of the RBAC-QoL Study.International journal of tryptophan research : IJTR · 2026Article
- The effects of VR/AR/MR-based interventions on symptom management among adult cancer survivors receiving active treatments: a systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2025Review
- Longitudinal symptom network patterns in cancer patients during the end of life.Scientific reports · 2025Article
- Step count and symptom severity during cancer treatment using the Symptom Care at Home digital platform.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Cross-Cultural Adaptation and Psychometric Properties of the Persian Version of the Spiritual Distress Scale (P-SDS) Among Older Adults with Cancer in Iran.Journal of religion and health · 2025Article
- Adherence to Exercise in People with Lung or Head and Neck Cancer: Self-Reported Symptoms and Motivation During Cancer Treatment Need to Be Considered.Journal of clinical medicine · 2024Article
- Investigation of screening questions to identify insomnia in cancer patients.Scientific reports · 2024Article
- Determining the cut-off value for the Minimal Documentation System (MIDOS2) screening tool to initiate specialized palliative care based on patient's subjective need for palliative support and symptom burden in inpatients with advanced cancer.Journal of cancer research and clinical oncology · 2024Article
- App-Based Lifestyle Intervention (PINK! Coach) in Breast Cancer Patients-A Real-World-Data Analysis.Cancers · 2024Article
- Evaluation of factors predicting the benefit from systemic oncological treatment for severely ill hospitalized patients: a retrospective study.BMC palliative care · 2023Observational
- Development of a keyword library for capturing PRO-CTCAE-focused "symptom talk" in oncology conversations.JAMIA open · 2023Article
- [Living Actively with Cancer - Recommendations for a Healthy Life Style: Needs Assessment and Design of Multimedia Patient Information].Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2023Article
- Dyspnea in Oncological Patients: a Brain Teaser.European cardiology · 2023Review
- Less, but not gone-gluten-free diet effects on fatigue in celiac disease: a prospective controlled study.Frontiers in medicine · 2023Article
- In Reply.Deutsches Arzteblatt international · 2021Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer patients account for a large segment of the German healthcare system, with a 5-year prevalence of around 1.7 million persons. Advances in oncological treatment, now frequently performed on an outpatient basis, are granting many of these individuals a longer life span. At the same time, cancer patients often suffer disease-related symptoms and adverse effects from their tumor treatment, which may strongly impair their quality of life despite the improved techniques for management of side effects.
methodsThis review is based on a selective literature search of the PubMed and Cochrane Library databases carried out in December 2019 and January 2020. Special attention was paid to guidelines, expert opinions, and recommendations from professional societies.
resultsAlongside decreased well-being, cancer patients often suffer from fatigue (70-100%), loss of appetite (6-53%), pain (30-80 %), and dyspnea (10-70%). The prevalence and severity of the symptoms varies depending on the tumor entity and the patient's sex. A meta-analysis showed that besides causal treatment, physical activity achieves moderately strong effects in tumor-associated fatigue syndrome (Cohen's d = 0.30 [0.25; 0.36]). The WHO recommends early use of opioids in tumor-associated pain. A meta-analysis of randomized trials described symptom relief by means of opioids also in dyspnea (standardized mean difference: -0.32 [-0.53; -0.10]). Increasingly, guidelines are recommending regular palliative medical symptom screening.
conclusionRegular documentation of symptoms in outpatients offers the opportunity for targeted management of symptoms during treatment with the involvement of various disciplines such as palliative medicine, exercise therapy, and psychotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.