Evidence map›Paper›PMID 33531030›Full record

ArticleActa veterinaria Scandinavica2021

Isolation of equid alphaherpesvirus 3 from a horse in Iceland with equine coital exanthema.

Lilja Thorsteinsdóttir, Gunnar Örn Guðmundsson, Höskuldur Jensson, Sigurbjörg Torsteinsdóttir, Vilhjálmur Svansson

Open access · goldAbstract readCase Reports
In one paragraph

Article in Acta veterinaria Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lilja ThorsteinsdóttirInstitute for Experimental Pathology, Biomedical Centre, University of Iceland, Keldur, Keldnavegur 3, 112, Reykjavík, Iceland. liljatho@hi.is.ORCID http://orcid.org/0000-0003-2410-2960
Gunnar Örn Guðmundsson, Ásvegur 10, Hvanneyri, 311, Borgarnes, Iceland.
Höskuldur JenssonNautabú, Hjaltadal, 551, Sauðárkrókur, Iceland.
Sigurbjörg TorsteinsdóttirInstitute for Experimental Pathology, Biomedical Centre, University of Iceland, Keldur, Keldnavegur 3, 112, Reykjavík, Iceland.
Vilhjálmur SvanssonInstitute for Experimental Pathology, Biomedical Centre, University of Iceland, Keldur, Keldnavegur 3, 112, Reykjavík, Iceland.
University of Iceland · ISAgricultural University of Iceland · IS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Equine coital exanthema (ECE) caused by equid alphaherpesvirus 3 (EHV-3) is a contagious venereal disease. It is characterized by the formation of papules, vesicles, pustules and ulcers on the external genitals of both mares and stallions. The Icelandic horse is the only breed in Iceland and has lived isolated in the country for over 1000 years. Three types of equine herpesviruses (EHV) have been found in Iceland, EHV-4, EHV-2 and EHV-5, while EHV-1 has never been detected. Symptoms resembling ECE have previous been observed in horses in Iceland, arousing suspicion of EHV-3 infection, but this has never been confirmed using virological methods. Samples were collected from a mare with papules on the vulva and inoculated in primary equine kidney cells. Cytopathic effects developed as rounded cells and syncytial formation. Polymerase chain reaction and sequencing of the partial glycoprotein G and DNA polymerase genes identified the isolated virus as EHV-3. On the basis of the findings, EHV-3 infection was verified for the first time in the native Icelandic horse population.

Indexed as

AnimalsDiagnosis, DifferentialFemaleHerpesviridae InfectionsHerpesvirus 3, EquidHorse DiseasesHorsesIcelandDNA polymerase geneGlycoprotein GPCRSequencingTitrationVirus isolation

Identifiers

PMID33531030
PMCPMC7856744
OpenAlexW3128287871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.