Evidence map›Paper›PMID 33530837›Full record

ArticleThe International journal of artificial organs2022

Custodiol-MP for ex vivo lung perfusion - A comparison in a porcine model of donation after circulatory determination of death.

Katharina Kalka, Zoe Keldenich, Henning Carstens, Björn Walter, Ursula Rauen, Arjang Ruhparwar, Alexander Weymann, Markus Kamler, Gerald Reiner, Achim Koch

Open access · bronzeAbstract read
In one paragraph

Article in The International journal of artificial organs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Research advances in consistency and variability inJournal of thoracic disease · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Katharina KalkaDepartment of Thoracic and Cardiovascular Surgery, Division of Thoracic Transplantation, West German Heart Center, University Hospital Essen, Essen, Germany.ORCID https://orcid.org/0000-0002-1697-1843
Zoe KeldenichDepartment of Thoracic and Cardiovascular Surgery, Division of Thoracic Transplantation, West German Heart Center, University Hospital Essen, Essen, Germany.
Henning CarstensDepartment of Cardiothoracic Surgery, Center of Cardiology, University Hospital Cologne, Cologne, Nordrhein-Westfalen, Germany.
Björn WalterInstitut für Physiologische Chemie, Universitätsklinikum Essen, Essen, Nordrhein-Westfalen, Germany.
Ursula RauenInstitut für Physiologische Chemie, Universitätsklinikum Essen, Essen, Nordrhein-Westfalen, Germany.
Arjang RuhparwarDepartment of Thoracic and Cardiovascular Surgery, Division of Thoracic Transplantation, West German Heart Center, University Hospital Essen, Essen, Germany.
Alexander WeymannDepartment of Thoracic and Cardiovascular Surgery, Division of Thoracic Transplantation, West German Heart Center, University Hospital Essen, Essen, Germany.
Markus KamlerDepartment of Thoracic and Cardiovascular Surgery, Division of Thoracic Transplantation, West German Heart Center, University Hospital Essen, Essen, Germany.
Gerald ReinerDepartment of Veterinary Clinical Sciences, Swine Clinic, Justus-Liebig-University, Giessen, Hessen, Germany.
Achim KochDepartment of Thoracic and Cardiovascular Surgery, Division of Thoracic Transplantation, West German Heart Center, University Hospital Essen, Essen, Germany.ORCID https://orcid.org/0000-0002-1616-4873
West German Heart and Vascular Center Essen · DEEssen University Hospital · DEJustus-Liebig-Universität Gießen · DEUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEx vivo lung perfusion (EVLP) is an established technique to evaluate and eventually recondition lungs prior to transplantation. Custodiol-MP (C-MP) solution is a new solution, designed for clinical machine perfusion, that has been used for kidneys. The aim of this study was to compare the effects of EVLP with Custodiol-MP on lung functional outcomes to the gold standard of EVLP with Steen Solution™. MATERIAL AND

methodsIn a porcine EVLP model of DCDD (Donation after Circulatory Determination of Death), lungs were perfused with Steen Solution™ (SS,

resultsOxygenation capacity differed significantly between groups (averaged over 4 h: SS 274 ± 178 mmHg; C-MP 284 ± 151 mmHg

Indexed as

Lung TransplantationAnimalsDeathExtracorporeal CirculationLungOrgan PreservationPerfusionSwineaffordable artificial organsanimal modelsartificial lungCustodiol-MPex vivo lung perfusionLung transplantmechanical ventilationorgan preservationpulmonary function

Identifiers

PMID33530837
PMCPMC8777315
OpenAlexW3128321911

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.