Evidence map›Paper›PMID 33530836›Full record

ArticleJournal of dental research2021

Dissecting the Role of VicK Phosphatase in Aggregation and Biofilm Formation of

S Wang, L Long, X Yang, Y Qiu, T Tao, X Peng, Y Li, A Han, D B Senadheera, J S Downey and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Key virulence genes associated withFrontiers in oral health · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Anticariogenic activity of marine brown algaeFrontiers in cellular and infection microbiology · 2024
    Article
  7. Inhibitory Effect of Adsorption ofInternational journal of molecular sciences · 2023
    Article
  8. Systematic analysis of lysine malonylation inFrontiers in cellular and infection microbiology · 2022
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

S WangState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
L LongState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
X YangState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Y QiuState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
T TaoState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
X PengState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.ORCID 0000-0001-8479-5944
Y LiState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
A HanState Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen University Xiang'an Campus, Xiamen, Fujian, China.
D B SenadheeraSchool of Dental Medicine, Stony Brook University, Stony Brook, NY, USA.
J S DowneyDivision of Biomedical Sciences, Herman Ostrow School of Dentistry of University of Southern California, Los Angeles, CA, USA.
S D GoodmanCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
X ZhouState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
D G CvitkovitchDental Research Institute, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.
Sichuan University · CNNationwide Children's Hospital · USStony Brook School · USUniversity of Southern California · USUniversity of Toronto · CAXiamen University · CN

Funding

Regulation of gtf Gene Expression in S mutansR01DE013965 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GOODMAN, STEVEN D · 2001 to 2005
$1.3M
NIDCR NIH HHS R01 DE013965
6 · The paper itself

Abstract

VicRK (WalRK or YycFG) is a conserved 2-component regulatory system (TCS) that regulates cell division, cell wall biosynthesis, and homeostasis in low-GC Gram-positive bacteria. VicRK is also associated with biofilm formation of

Indexed as

Phosphoric Monoester HydrolasesStreptococcus mutansBacterial ProteinsBiofilmsGene Expression Regulation, BacterialVirulenceBacterial ProteinsPhosphoric Monoester Hydrolasesagglutininscariesgene expression regulationglucosyltransferasehistidine protein kinasepolysaccharides

Identifiers

PMID33530836
PMCPMC9290112
OpenAlexW3129135339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.