Evidence map›Paper›PMID 33530703›Full record

ArticleCirculation research2021

Atherosclerosis Regression and Cholesterol Efflux in Hypertriglyceridemic Mice.

Tatjana Josefs, Debapriya Basu, Tomas Vaisar, Britt Arets, Jenny E Kanter, Lesley-Ann Huggins, Yunying Hu, Jianhua Liu, Noemie Clouet-Foraison, Jay W Heinecke and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. β-carotene accelerates the resolution of atherosclerosis in mice.bioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Review
  11. The Remnant Lipoprotein Hypothesis of Diabetes-Associated Cardiovascular Disease.Arteriosclerosis, thrombosis, and vascular biology · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Addressing dyslipidemic risk beyond LDL-cholesterol.The Journal of clinical investigation · 2022
    Review
  16. Review
  17. Macrophages in Atheromatous Plaque Developmental Stages.Frontiers in cardiovascular medicine · 2022
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 5 countries.

Tatjana Josefs *Division of Cardiology (T.J., J.L., E.A.F.), Department of Medicine, New York University School of Medicine.
Debapriya Basu *Division of Endocrinology, Diabetes and Metabolism (D.B., L.-A.H., Y.H., I.J.G.), Department of Medicine, New York University School of Medicine.
Tomas VaisarDepartment of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle (T.V., J.E.K., N.C.-F., J.W.H., K.E.B.).
Britt Arets
Jenny E KanterDepartment of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle (T.V., J.E.K., N.C.-F., J.W.H., K.E.B.).
Lesley-Ann HugginsDivision of Endocrinology, Diabetes and Metabolism (D.B., L.-A.H., Y.H., I.J.G.), Department of Medicine, New York University School of Medicine.
Yunying HuDivision of Endocrinology, Diabetes and Metabolism (D.B., L.-A.H., Y.H., I.J.G.), Department of Medicine, New York University School of Medicine.
Jianhua LiuDivision of Cardiology (T.J., J.L., E.A.F.), Department of Medicine, New York University School of Medicine.
Noemie Clouet-ForaisonDepartment of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle (T.V., J.E.K., N.C.-F., J.W.H., K.E.B.).
Jay W HeineckeDepartment of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle (T.V., J.E.K., N.C.-F., J.W.H., K.E.B.).
Karin E BornfeldtDepartment of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle (T.V., J.E.K., N.C.-F., J.W.H., K.E.B.).
Ira J GoldbergDivision of Endocrinology, Diabetes and Metabolism (D.B., L.-A.H., Y.H., I.J.G.), Department of Medicine, New York University School of Medicine.
Edward A FisherDivision of Cardiology (T.J., J.L., E.A.F.), Department of Medicine, New York University School of Medicine.
Diabetes Australia · AUTwitter (United States) · USUniversity of Washington · USJilin Jianzhu University · CNMaastricht University Medical Centre · NLNew York University · USVaisala (United States) · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
Stable Isotope and Metabolomics CoreP60DK020541 · NIDDK · YESHIVA UNIVERSITY · PI PESSIN, JEFFREY E. · 1986 to 2014
$29.8M
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7M
Resolving Macrophage Inflammation in Atherosclerotic Plaques and Other Sites in Insulin ResistanceP01HL131481 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANN MARIE SCHMIDT · 2017 to 2026
$27.3M
Role of Serum Amyloid A in Diabetic Vascular DiseaseP01HL092969 · NHLBI · UNIVERSITY OF WASHINGTON · PI BORNFELDT, KARIN E. · 2008 to 2019
$23.5M
Triglycerides, Diabetes and Cardiovascular DiseaseP01HL151328 · NHLBI · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 2020 to 2026
$19.6M
Molecular Regulation of Atherosclerosis Regression - RenewalR01HL084312 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FISHER, EDWARD A · 2006 to 2024
$11.4M
Pathways of Tissue Lipid UptakeR01HL045095 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ABUMRAD, NADA A., GOLDBERG, IRA J · 1991 to 2024
$6.9M
Mechanisms of Fatty Acid Uptake By Cardiac MuscleR01HL073029 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GOLDBERG, IRA J · 2003 to 2021
$6.8M
Identifying new strategies for prevention of cardiovascular complications of diabetesR35HL150754 · NHLBI · UNIVERSITY OF WASHINGTON · PI BORNFELDT, KARIN E · 2020 to 2025
$6.2M
HDL composition/function and cardiovascular risk in youths with diabetesR01HL144558 · NHLBI · UNIVERSITY OF WASHINGTON · PI VAISAR, TOMAS · 2019 to 2022
$2.8M
HDL and atherosclerosis regressionR01HL129433 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FISHER, EDWARD A, MOORE, KATHRYN J · 2016 to 2019
$2.4M
NHLBI NIH HHS P01 HL092969NHLBI NIH HHS P01 HL131481NHLBI NIH HHS P01 HL151328NHLBI NIH HHS R01 HL045095NHLBI NIH HHS R01 HL073029NHLBI NIH HHS R01 HL084312NHLBI NIH HHS R01 HL129433NHLBI NIH HHS R01 HL144558NHLBI NIH HHS R35 HL150754NIDDK NIH HHS P30 DK017047NIDDK NIH HHS P30 DK020541NIDDK NIH HHS P60 DK020541
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AnimalsAtherosclerosisATP Binding Cassette Transporter 1Cells, CulturedCholesterol Ester Transfer ProteinsCholesterol, HDLHumansHypertriglyceridemiaLipoprotein LipaseMacrophagesMiceMice, Inbred C57BLAbca1 protein, mouseATP Binding Cassette Transporter 1CETP protein, humanCholesterol Ester Transfer ProteinsCholesterol, HDLLipoprotein Lipaseatherosclerosiscardiovascular diseaselipoprotein lipaselipoproteinsmacrophagestriglyceride

Identifiers

PMID33530703
PMCPMC7979499
OpenAlexW3128562190

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.