Evidence map›Paper›PMID 33530702›Full record

ArticleCirculation research2021

BCL11B Regulates Arterial Stiffness and Related Target Organ Damage.

Jeff Arni C Valisno, Joel May, Kuldeep Singh, Eric Y Helm, Lisia Venegas, Enkhjargal Budbazar, Jena B Goodman, Christopher J Nicholson, Dorina Avram, Richard A Cohen and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Jeff Arni C ValisnoVascular Biology Section, Department of Medicine, Boston University School of Medicine, MA (J.A.C.V., J.M., L.V., E.B., J.B.G., R.A.C., F.S.).
Joel MayVascular Biology Section, Department of Medicine, Boston University School of Medicine, MA (J.A.C.V., J.M., L.V., E.B., J.B.G., R.A.C., F.S.).
Kuldeep SinghDepartment of Health Sciences, Sargent College, Boston University, MA (K.S., C.J.N., K.G.M.).
Eric Y HelmDepartment of Anatomy and Cell Biology, College of Medicine, University of Florida, Gainesville (E.Y.H., D.A.).
Lisia VenegasVascular Biology Section, Department of Medicine, Boston University School of Medicine, MA (J.A.C.V., J.M., L.V., E.B., J.B.G., R.A.C., F.S.).
Enkhjargal BudbazarVascular Biology Section, Department of Medicine, Boston University School of Medicine, MA (J.A.C.V., J.M., L.V., E.B., J.B.G., R.A.C., F.S.).
Jena B GoodmanVascular Biology Section, Department of Medicine, Boston University School of Medicine, MA (J.A.C.V., J.M., L.V., E.B., J.B.G., R.A.C., F.S.).
Christopher J NicholsonDepartment of Health Sciences, Sargent College, Boston University, MA (K.S., C.J.N., K.G.M.).
Dorina AvramDepartment of Anatomy and Cell Biology, College of Medicine, University of Florida, Gainesville (E.Y.H., D.A.).
Richard A CohenVascular Biology Section, Department of Medicine, Boston University School of Medicine, MA (J.A.C.V., J.M., L.V., E.B., J.B.G., R.A.C., F.S.).
Gary F MitchellCardiovascular Engineering, Norwood, MA (G.F.M.).
Kathleen G MorganDepartment of Health Sciences, Sargent College, Boston University, MA (K.S., C.J.N., K.G.M.).
Francesca SetaVascular Biology Section, Department of Medicine, Boston University School of Medicine, MA (J.A.C.V., J.M., L.V., E.B., J.B.G., R.A.C., F.S.).
Boston University · USMitchell College · USMoffitt Cancer Center · USUniversity of Florida · US

Funding

Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI CORKEY, BARBARA E. · 1992 to 2021
$25.0M
Multidisciplinary Training in Cardiovascular ResearchT32HL007224 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAMBURG, NAOMI MIRIAM, WAINFORD, RICHARD DAVID · 1985 to 2020
$12.3M
Role of Bcl11b in CD4+ T cells and innate lymphoid cellsR01AI067846 · NIAID · UNIVERSITY OF FLORIDA · PI AVRAM, DORINA · 2007 to 2023
$6.2M
Ventricular Vascular Coupling: Correlates and PrognosisR01HL080124 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN S · 2005 to 2009
$3.4M
The role of Bcl11b in dementia associated with Parkinsons diseaseR01HL136311 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SETA, FRANCESCA · 2018 to 2022
$2.8M
Actin and focal adhesion remodeling as therapeutic targets in cardiovascular diseaseR01AG053274 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MORGAN, KATHLEEN G · 2017 to 2021
$2.7M
Vascular Stiffness as a Precursor of Hypertension in a Middle-aged CohortR01HL126136 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MITCHELL, GARY FRANK, RAMACHANDRAN, VASAN S · 2015 to 2018
$2.6M
Aortic Dysfunction, Pulsatile Stress and Target Organ Damage in FraminghamR01HL107385 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MITCHELL, GARY FRANK, RAMACHANDRAN, VASAN S · 2011 to 2014
$2.6M
Vascular Function in the Framingham Third GenerationR01HL070100 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J. · 2002 to 2005
$2.4M
Aortic Stiffness and Hypertension in Obese MiceR01HL105287 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COHEN, RICHARD A · 2010 to 2013
$1.6M
The Role of the Cytoskeleton in Vascular AgingR21AG050599 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MORGAN, KATHLEEN G · 2015 to 2016
$445k
NHLBI NIH HHS R01 HL070100NHLBI NIH HHS R01 HL080124NHLBI NIH HHS R01 HL105287NHLBI NIH HHS R01 HL107385NHLBI NIH HHS R01 HL126136NHLBI NIH HHS R01 HL136311NHLBI NIH HHS T32 HL007224NIAID NIH HHS R01 AI067846NIA NIH HHS R01 AG053274NIA NIH HHS R21 AG050599NIDDK NIH HHS P30 DK046200
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Vascular StiffnessActinsAdolescentAdultAnimalsAortaCalcineurinCell Adhesion MoleculesCell LineCells, CulturedCyclic GMP-Dependent Protein Kinase Type IHumansMaleMiceMice, Inbred C57BLMicrofilament ProteinsActinsBcl11b protein, mouseCalcineurinCell Adhesion MoleculesCyclic GMP-Dependent Protein Kinase Type IMicrofilament ProteinsPhosphoproteinsRepressor ProteinsTumor Suppressor ProteinsVasodilator-Stimulated Phosphoproteinactinsblood pressurecalcineurinphosphorylationvascular smooth musclevascular stiffness

Identifiers

PMID33530702
PMCPMC7969164
OpenAlexW3127913723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.