Evidence map›Paper›PMID 33530700›Full record

ArticleCirculation research2021

Microfibrillar-Associated Protein 4 Regulates Stress-Induced Cardiac Remodeling.

Lisa E Dorn, William Lawrence, Jennifer M Petrosino, Xianyao Xu, Thomas J Hund, Bryan A Whitson, Matthew S Stratton, Paul M L Janssen, Peter J Mohler, Anders Schlosser and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  6. IdentifyingBiomolecules · 2024
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  10. Research progress of autophagy in heart failure.American journal of translational research · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Lisa E DornPhysiology and Cell Biology (L.E.D., W.L., J.M.P., M.S.S., P.M.L.J., P.J.M., F.A.), The Ohio State University Wexner Medical Center, Columbus.
William LawrencePhysiology and Cell Biology (L.E.D., W.L., J.M.P., M.S.S., P.M.L.J., P.J.M., F.A.), The Ohio State University Wexner Medical Center, Columbus.
Jennifer M PetrosinoPhysiology and Cell Biology (L.E.D., W.L., J.M.P., M.S.S., P.M.L.J., P.J.M., F.A.), The Ohio State University Wexner Medical Center, Columbus.
Xianyao XuBiomedical Engineering, The Ohio State University, Columbus (X.X., T.J.H.).
Thomas J HundBiomedical Engineering, The Ohio State University, Columbus (X.X., T.J.H.).
Bryan A WhitsonBob and Corrine Frick Center for Heart Failure and Arrhythmia (B.A.W., P.J.M.), The Ohio State University Wexner Medical Center, Columbus.
Matthew S StrattonPhysiology and Cell Biology (L.E.D., W.L., J.M.P., M.S.S., P.M.L.J., P.J.M., F.A.), The Ohio State University Wexner Medical Center, Columbus.
Paul M L JanssenPhysiology and Cell Biology (L.E.D., W.L., J.M.P., M.S.S., P.M.L.J., P.J.M., F.A.), The Ohio State University Wexner Medical Center, Columbus.
Peter J MohlerPhysiology and Cell Biology (L.E.D., W.L., J.M.P., M.S.S., P.M.L.J., P.J.M., F.A.), The Ohio State University Wexner Medical Center, Columbus.
Anders SchlosserCancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense (A.S., G.L.S.).
Grith L SorensenCancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense (A.S., G.L.S.).
Federica AccorneroPhysiology and Cell Biology (L.E.D., W.L., J.M.P., M.S.S., P.M.L.J., P.J.M., F.A.), The Ohio State University Wexner Medical Center, Columbus.
The Ohio State University Wexner Medical Center · USUniversity of Southern Denmark · DKChina XD Group (China) · CNThe Ohio State University · US

Funding

Post-transcriptional regulation of cardiac hypertrophyR01HL136951 · NHLBI · OHIO STATE UNIVERSITY · PI Federica Accornero · 2017 to 2026
$4.7M
Frequency-dependent modulation of cardiac myofilament function in health/diseaseR01HL113084 · NHLBI · OHIO STATE UNIVERSITY · PI JANSSEN, PAULUS ML · 2012 to 2023
$4.6M
Training To Provide the Knowledge, Skills, and Culture To the Next Generation of Cardiovascular ScientistsT32HL134616 · NHLBI · OHIO STATE UNIVERSITY · PI Brandon J Biesiadecki, Jill A Rafael-Fortney · 2017 to 2026
$2.6M
Mechanistic characterization of a new master regulator of cardiac virus infectionsR01HL154001 · NHLBI · OHIO STATE UNIVERSITY · PI ACCORNERO, FEDERICA, YOUNT, JACOB · 2020 to 2023
$2.3M
CaMKII-dependent regulation of cardiac excitabilityR01HL114893 · NHLBI · OHIO STATE UNIVERSITY · PI HUND, THOMAS JEFFREY · 2012 to 2016
$1.9M
Spectrin-based regulation of cardiac remodeling and heart failureR01HL135096 · NHLBI · OHIO STATE UNIVERSITY · PI HUND, THOMAS JEFFREY · 2017 to 2020
$1.6M
BEX1 and the control of protein translation in cardiac hypertrophyR00HL121284 · NHLBI · OHIO STATE UNIVERSITY · PI ACCORNERO, FEDERICA · 2016 to 2018
$727k
BEX1 and the control of protein translation in cardiac hypertrophyK99HL121284 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI ACCORNERO, FEDERICA · 2014 to 2015
$262k
The role of N-6-adenosine and its writer, METTL3, in the cardiac hypertrophic responseF30HL145955 · NHLBI · OHIO STATE UNIVERSITY · PI DORN, LISA E. · 2019 to 2022
$178k
NHLBI NIH HHS F30 HL145955NHLBI NIH HHS K99 HL121284NHLBI NIH HHS R00 HL121284NHLBI NIH HHS R01 HL113084NHLBI NIH HHS R01 HL114893NHLBI NIH HHS R01 HL135096NHLBI NIH HHS R01 HL136951NHLBI NIH HHS R01 HL154001NHLBI NIH HHS T32 HL134616
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AngiotensinsAnimalsAortaCardiomegalyCarrier ProteinsCells, CulturedConstrictionExtracellular Matrix ProteinsFemaleGlycoproteinsHumansIntegrinsMaleMiceMice, Inbred C57BLMyocytes, CardiacAngiotensinsCarrier ProteinsExtracellular Matrix ProteinsGlycoproteinsIntegrinsMFAP4 protein, mousePhenylephrineTransforming Growth Factor betaextracellular matrixheart failureintegrinrisk factorventricular remodeling

Identifiers

PMID33530700
PMCPMC8188624
OpenAlexW3126337532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.